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Found 25 with Last Name = 'boettcher' and Initial = 'br'
TargetGlutamine synthetase(Homo sapiens (Human))
Chevron Chemical

LigandPNGBDBM85288(Phosphinothricin analog, 1 (L Isomer))
Affinity DataKi:  0.220nMpH: 7.0Assay Description:The enzyme was assayed at pH 7.0 using the pyruvate kinase/lactate dehydroenase coupling system.More data for this Ligand-Target Pair
In DepthDetails
TargetGlutamine synthetase(Homo sapiens (Human))
Chevron Chemical

LigandPNGBDBM85291(Phosphinothricin analog, 4 (D,L Isomer))
Affinity DataKi:  0.470nMpH: 7.0Assay Description:The enzyme was assayed at pH 7.0 using the pyruvate kinase/lactate dehydroenase coupling system.More data for this Ligand-Target Pair
In DepthDetails
TargetGlutamine synthetase(Homo sapiens (Human))
Chevron Chemical

LigandPNGBDBM85293(Phosphinothricin analog, 6 (D,L Isomer))
Affinity DataKi:  5nMpH: 7.0Assay Description:The enzyme was assayed at pH 7.0 using the pyruvate kinase/lactate dehydroenase coupling system.More data for this Ligand-Target Pair
In DepthDetails
TargetGlutamine synthetase(Homo sapiens (Human))
Chevron Chemical

LigandPNGBDBM85290(Phosphinothricin analog, 3 (L Isomer))
Affinity DataKi:  45nMpH: 7.0Assay Description:The enzyme was assayed at pH 7.0 using the pyruvate kinase/lactate dehydroenase coupling system.More data for this Ligand-Target Pair
In DepthDetails
TargetGlutamine synthetase(Homo sapiens (Human))
Chevron Chemical

LigandPNGBDBM85289(Phosphinothricin analog, 2 (D,L mixture))
Affinity DataKi:  140nMpH: 7.0Assay Description:The enzyme was assayed at pH 7.0 using the pyruvate kinase/lactate dehydroenase coupling system.More data for this Ligand-Target Pair
In DepthDetails
TargetXaa-Pro dipeptidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285931(2-((1R,2R)-2-Carboxy-cyclopentyl)-2-oxo-ethyl-ammo...)
Affinity DataKi:  270nMAssay Description:Inhibitory activity against porcine kidney prolidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamine synthetase(Homo sapiens (Human))
Chevron Chemical

LigandPNGBDBM85292(Phosphinothricin analog, 5 (D,L Isomer))
Affinity DataKi:  310nMpH: 7.0Assay Description:The enzyme was assayed at pH 7.0 using the pyruvate kinase/lactate dehydroenase coupling system.More data for this Ligand-Target Pair
In DepthDetails
TargetXaa-Pro dipeptidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50240386(5-amino-4-oxopentanoic acid | 5-aminolevulinic aci...)
Affinity DataKi:  9.60E+5nMAssay Description:Inhibitory activity against porcine kidney prolidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetXaa-Pro dipeptidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285933(2-((1R,2R)-2-Carboxy-cyclohexyl)-2-oxo-ethyl-ammon...)
Affinity DataKi:  1.10E+6nMAssay Description:Inhibitory activity against porcine kidney prolidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285934(1-[2-((S)-3-Benzoylamino-2-oxo-4-phenyl-butylamino...)
Affinity DataIC50:  70nMAssay Description:Inhibitory activity against angiotensin converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(CHEMBL102521 | N-hydroxyglycine derivative)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(CHEMBL102521 | N-hydroxyglycine derivative)
Affinity DataIC50:  230nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(CHEMBL102521 | N-hydroxyglycine derivative)
Affinity DataIC50:  950nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 1.2 mM NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290880(CHEMBL318550 | [Hydroxy-((2E,6E)-3,7,11-trimethyl-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50059865(4,8,12-trimethyl-(3E,7E)-3,7,11-tridecatrienylhydr...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285932(1-[2-((S)-2-Benzoylamino-3-phenyl-propionylamino)-...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibitory activity against angiotensin converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290883(CHEMBL102874 | N-hydroxyglycine derivative)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290887(CHEMBL99892 | N-hydroxyglycine derivative)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290888(CHEMBL102520 | N-hydroxyglycine derivative)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290881(CHEMBL319416 | N-hydroxyglycine derivative)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290885(CHEMBL99944 | N-hydroxyglycine derivative)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(CHEMBL102521 | N-hydroxyglycine derivative)
Affinity DataIC50:  5.70E+4nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290886(CHEMBL102570 | N-hydroxyglycine derivative)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290879(CHEMBL102600 | [Hydroxy-((2E,6E)-3,7,11-trimethyl-...)
Affinity DataIC50:  5.23E+5nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290884(((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylami...)
Affinity DataIC50:  6.40E+5nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article