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Found 29 with Last Name = 'culp' and Initial = 'js'
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50380246(CHEMBL2017214)
Affinity DataIC50:  12nMAssay Description:Inhibition of KHK (unknown origin) using D-fructose as substrate after 60 mins in presence of ATP by LC-MS analysisMore data for this Ligand-Target Pair
TargetKetohexokinase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241178(CHEMBL4070442)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant rat N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins fol...More data for this Ligand-Target Pair
TargetKetohexokinase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241178(CHEMBL4070442)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant rat N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins fol...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241178(CHEMBL4070442)
Affinity DataIC50:  389nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK-A expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241178(CHEMBL4070442)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK-A expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241178(CHEMBL4070442)
Affinity DataIC50:  450nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK-C expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241178(CHEMBL4070442)
Affinity DataIC50:  450nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK-C expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349755(CHEMBL1809182 | US8822447, 50 | US9771375, Example...)
Affinity DataIC50:  590nMAssay Description:Inhibition of KHK (unknown origin) using D-fructose as substrate after 60 mins in presence of ATP by LC-MS analysisMore data for this Ligand-Target Pair
TargetKetohexokinase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241195(CHEMBL4063606)
Affinity DataIC50:  640nMAssay Description:Inhibition of recombinant rat N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241195(CHEMBL4063606)
Affinity DataIC50:  646nMAssay Description:Inhibition of recombinant rat N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241195(CHEMBL4063606)
Affinity DataIC50:  670nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241195(CHEMBL4063606)
Affinity DataIC50:  676nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241197(CHEMBL4072209)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241209(CHEMBL4101660)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241209(CHEMBL4101660)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241200(CHEMBL4085228)
Affinity DataIC50:  1.68E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241212(CHEMBL4092972)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241212(CHEMBL4092972)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241205(CHEMBL1463512)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241205(CHEMBL1463512)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241207(CHEMBL4086173)
Affinity DataIC50:  1.18E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241207(CHEMBL4086173)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241206(CHEMBL1500542)
Affinity DataIC50:  3.16E+5nMAssay Description:Binding constant against dopamine receptor D2 (in vitro)More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241206(CHEMBL1500542)
Affinity DataIC50:  3.19E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241201(CHEMBL4074975)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241206(CHEMBL1500542)
Affinity DataKd:  6.20E+4nMAssay Description:Binding affinity to full length recombinant human biotin-labeled KHK by SPR assayMore data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241205(CHEMBL1463512)
Affinity DataKd:  4.40E+4nMAssay Description:Binding affinity to full length recombinant human biotin-labeled KHK by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241201(CHEMBL4074975)
Affinity DataKd:  1.03E+5nMAssay Description:Binding affinity to full length recombinant human biotin-labeled KHK by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241207(CHEMBL4086173)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity to full length recombinant human biotin-labeled KHK by SPR assayMore data for this Ligand-Target Pair