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Found 410 with Last Name = 'engh' and Initial = 'ra'
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  6nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50073316(CHEMBL114715 | INOGATRAN | {(R)-1-Cyclohexylmethyl...)
Affinity DataKi:  15nMAssay Description:The inhibitory activity of the compound was tested against thrombin (IIa)More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068485((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  21nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070629(4-[2-(3-Benzenesulfonylamino-5-methyl-phenoxy)-eth...)
Affinity DataKi:  23nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068501((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  26nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068490(CHEMBL146940 | [4-(1-Carbamimidoyl-piperidin-4-ylo...)
Affinity DataKi:  28nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068493((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  30nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068494((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  30nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068488((S)-3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-...)
Affinity DataKi:  40nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068487(CHEMBL148357 | [4-(1-Carbamimidoyl-piperidin-4-ylo...)
Affinity DataKi:  44nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068506((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  55nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070596(CHEMBL282549 | N-Methyl-N-{3-[2-(pyridin-4-ylamino...)
Affinity DataKi:  70nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068499((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  80nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068493((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  80nMAssay Description:The inhibition constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068502((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  100nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50368984(CHEMBL4164814)
Affinity DataKi:  104nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50391956(CHEMBL2152265)
Affinity DataKi:  158nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070633(CHEMBL289790 | N-[3-(4-Guanidino-butoxy)-5-methyl-...)
Affinity DataKi:  180nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068484((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  200nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068487(CHEMBL148357 | [4-(1-Carbamimidoyl-piperidin-4-ylo...)
Affinity DataKi:  200nMAssay Description:The inhibition constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068486(CHEMBL147988 | [4-((S)-1-Carbamimidoyl-pyrrolidin-...)
Affinity DataKi:  200nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068485((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  200nMAssay Description:The inhibition constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289376(2-(Naphthalene-2-sulfonylamino)-N-[(R)-1-(piperidi...)
Affinity DataKi:  200nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068500(CHEMBL344309 | [4-((S)-1-Carbamimidoyl-pyrrolidin-...)
Affinity DataKi:  200nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068491((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  200nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068501((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  200nMAssay Description:The inhibition constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068507((S)-3-{4-[(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoq...)
Affinity DataKi:  200nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068490(CHEMBL146940 | [4-(1-Carbamimidoyl-piperidin-4-ylo...)
Affinity DataKi:  200nMAssay Description:The inhibition constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50066047(2-Benzyl-N-hydroxy-2-methyl-N'-(3-phenyl-propyl)-m...)
Affinity DataKi:  240nMAssay Description:Inhibition of human neutrophil collagenase (Matrix metalloproteinase-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50341228(1-(4-fluoro-2-(trifluoromethyl)phenyl)-9-(1H-pyraz...)
Affinity DataKi:  252nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetNeutrophil collagenase(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50066051(CHEMBL105352 | Indan-2,2-dicarboxylic acid hydroxy...)
Affinity DataKi:  300nMAssay Description:Inhibition of human neutrophil collagenase (Matrix metalloproteinase-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070632(4-[2-(3-Benzenesulfonylamino-phenoxy)-ethylamino]-...)
Affinity DataKi:  300nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070632(4-[2-(3-Benzenesulfonylamino-phenoxy)-ethylamino]-...)
Affinity DataKi:  300nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil collagenase(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50066049(2-Benzyl-N-hydroxy-2-methyl-N'-(4-phenyl-butyl)-ma...)
Affinity DataKi:  380nMAssay Description:Inhibition of human neutrophil collagenase (Matrix metalloproteinase-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50368980(CHEMBL4171089)
Affinity DataKi:  383nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068494((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  400nMAssay Description:The inhibition constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068495(CHEMBL148972 | [4-(1-Acetyl-piperidin-4-yloxy)-phe...)
Affinity DataKi:  400nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068505((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  400nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50368981(CHEMBL4168671)
Affinity DataKi:  575nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070622(CHEMBL40704 | N-[3-(3-Guanidino-propoxy)-5-methyl-...)
Affinity DataKi:  630nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073316(CHEMBL114715 | INOGATRAN | {(R)-1-Cyclohexylmethyl...)
Affinity DataKi:  675nMAssay Description:The inhibitory activity of the compound was tested against trypsinMore data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  690nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of bovine trypsin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50126700(4-Chloro-N-{3-[2-(pyridin-4-ylamino)-ethoxy]-pheny...)
Affinity DataKi:  700nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068486(CHEMBL147988 | [4-((S)-1-Carbamimidoyl-pyrrolidin-...)
Affinity DataKi:  1.00E+3nMAssay Description:The inhibition constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068498(CHEMBL342568 | [4-((S)-1-Allyl-pyrrolidin-3-yloxy)...)
Affinity DataKi:  1.00E+3nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50068496((2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-...)
Affinity DataKi:  1.00E+3nMAssay Description:The inhibition constant against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50066040(2,N-Dibenzyl-N'-hydroxy-2-methyl-malonamide | CHEM...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human neutrophil collagenase (Matrix metalloproteinase-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase(Oryctolagus cuniculus (Rabbit))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM15210(CHEMBL148333 | H-8 | Lopac-M-9656 | N-(2-methylami...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibitory constant against cAPK (PKA)More data for this Ligand-Target Pair
TargetNeutrophil collagenase(Homo sapiens (Human))
Boehringer Mannheim

Curated by ChEMBL
LigandPNGBDBM50066037(CHEMBL100678 | Indan-2,2-dicarboxylic acid benzyla...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human neutrophil collagenase (Matrix metalloproteinase-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289377(4-{3-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-phe...)
Affinity DataKi:  1.50E+3nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
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