Affinity DataKi: 0.0316nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1D expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.0500nMAssay Description:Affinity at alpha4-beta2 nACh receptors in rat brain (minus cerebellum) homogenates.More data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0525nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0575nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0661nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0676nMAssay Description:Displacement of [3H]prazosin from human adrenergic Alpha-1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0676nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0891nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0977nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.135nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.141nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M4 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1B expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.178nMAssay Description:Displacement of [3H]prazosin from human adrenergic Alpha-1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.178nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M2 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M5 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1B expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1A expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1B expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1A expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.309nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HeLa cell membranes after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1A expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.324nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Binding affinity of the compound towards Alpha-1A adrenergic receptor in bovine brainusing [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.363nMAssay Description:Displacement of [3H]RS79948-197 from human recombinant adrenergic alpha2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HeLa cell membranes after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.372nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.372nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Binding affinity of the compound towards Alpha-1A adrenergic receptor in bovine brainusing [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.389nMAssay Description:Displacement of [3H]prazosin from human adrenergic Alpha-1D expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1A expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1B expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1B expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HeLa cell membranes after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Displacement of [3H]prazosin from human recombinant alpha1A adrenergic receptor expressed in CHO cell membranes after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.427nMAssay Description:Displacement of [3H]prazosin from human adrenergic alpha1A expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.427nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1A adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]prazosin from human recombinant alpha1A adrenergic receptor expressed in CHO cell membranes after 30 minsMore data for this Ligand-Target Pair