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Found 41 with Last Name = 'grossmann' and Initial = 'tn'
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM17341((2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2...)
Affinity DataIC50:  400nMAssay Description:Displacement of fluorescent H-Abu-Arg-Pro-Phe-Lys-NH-FAM-NH2 peptide from XIAP BIR3 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50361465(CHEMBL1938611)
Affinity DataIC50:  560nMAssay Description:Displacement of fluorescent H-Abu-Arg-Pro-Phe-Lys-NH-FAM-NH2 peptide from XIAP BIR3 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50361466(CHEMBL1938613)
Affinity DataIC50:  650nMAssay Description:Displacement of fluorescent H-Abu-Arg-Pro-Phe-Lys-NH-FAM-NH2 peptide from XIAP BIR3 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246102(CHEMBL4096939)
Affinity DataIC50:  830nMAssay Description:Inhibition of TAMRA-labeled cRaf peptide binding to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246112(CHEMBL4069746)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of TAMRA-labeled cRaf peptide binding to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50361464(CHEMBL1938610)
Affinity DataIC50:  1.52E+3nMAssay Description:Displacement of fluorescent H-Abu-Arg-Pro-Phe-Lys-NH-FAM-NH2 peptide from XIAP BIR3 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246119(CHEMBL4068123)
Affinity DataIC50:  3.29E+3nMAssay Description:Inhibition of TAMRA-labeled cRaf peptide binding to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50436055(CHEMBL2397076)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of beta-catenin-mediated transcriptional activity in Wnt3a-stimulated human HeLa cells after 24 hrs by Dual-Glo luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50436054(CHEMBL2397077)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of beta-catenin-mediated transcriptional activity in Wnt3a-stimulated human HeLa cells after 24 hrs by Dual-Glo luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246102(CHEMBL4096939)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of 14-3-3zeta (unknown origin) in human U87 cells assessed as decrease in exogenous 14-3-3zeta-induced MMP1 mRNA levels after 24 hrs by RT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor 4(Homo sapiens)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50589362(CHEMBL5181203)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of His-tagged beta-catenin (134 to 668 residues)/CM-5 sensor chip immobilized N-terminal GST-tagged TCF4 interaction (unknown origin) prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246100(CHEMBL4076372)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246101(CHEMBL4096528)
Affinity DataKd:  99nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246102(CHEMBL4096939)
Affinity DataKd:  38nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50589364(CHEMBL5186135)
Affinity DataKd:  91nMAssay Description:Binding affinity to full-length beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246113(CHEMBL4098750)
Affinity DataKd:  6.40E+3nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246116(CHEMBL4063253)
Affinity DataKd:  59nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246117(CHEMBL4074169)
Affinity DataKd: >2.00E+4nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246118(CHEMBL4071395)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50589356(CHEMBL5194459)
Affinity DataKd:  13nMAssay Description:Binding affinity to human beta-catenin (134 to 665 residues) expressed in Escherichia coli BL21 assessed as dissociation constant incubated for 45 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50589357(CHEMBL5178667)
Affinity DataKd:  53nMAssay Description:Binding affinity to human beta-catenin (134 to 665 residues) expressed in Escherichia coli BL21 assessed as dissociation constant incubated for 45 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50589358(CHEMBL5178520)
Affinity DataKd:  123nMAssay Description:Binding affinity to full-length recombinant beta-catenin (unknown origin) assessed as dissociation constant by fluorescence polarisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50589359(CHEMBL5205469)
Affinity DataKd:  5nMAssay Description:Binding affinity to human beta-catenin (129 to 780 residues) expressed in Escherichia coli Rosetta blue assessed as dissociation constant using fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50589360(CHEMBL5180356)
Affinity DataKd:  5nMAssay Description:Binding affinity to human beta-catenin (129 to 780 residues) expressed in Escherichia coli Rosetta blue assessed as dissociation constant using fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50436058(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
Affinity DataKd:  450nMAssay Description:Binding affinity to beta-catenin (134 to 671 residues) (unknown origin) expressed in Escherichia coli BL21 assessed as dissociation constant by isoth...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50014132(CHEMBL2323032)
Affinity DataKd:  530nMAssay Description:Binding affinity to human beta-catenin (138 to 686 residues) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50589361(CHEMBL5181546)
Affinity DataKd:  420nMAssay Description:Binding affinity to beta-catenin (unknown origin) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50589362(CHEMBL5181203)
Affinity DataKd:  5.80E+5nMAssay Description:Binding affinity to CM-5 sensor chip immobilized His-tagged beta-catenin (134 to 668 residues) (unknown origin) expressed in Escherichia coli BL21 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50589363(CHEMBL5191201)
Affinity DataKd:  156nMAssay Description:Binding affinity to full-length beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246083(CHEMBL4079973)
Affinity DataKd:  9.00E+3nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246082(CHEMBL4073284)
Affinity DataKd: >2.00E+4nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246081(CHEMBL4100127)
Affinity DataKd: >2.00E+4nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246080(CHEMBL4061432)
Affinity DataKd:  350nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246079(CHEMBL4076293)
Affinity DataKd:  5.90E+3nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246078(CHEMBL4073158)
Affinity DataKd:  510nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50436058(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
Affinity DataKd:  450nMAssay Description:Inhibition of Tcf4 binding to beta-catenin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50436055(CHEMBL2397076)
Affinity DataKd:  13nMAssay Description:Binding affinity to human beta-catenin expressed in Escherichia coli BL21 after 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50436054(CHEMBL2397077)
Affinity DataKd:  53nMAssay Description:Binding affinity to human beta-catenin expressed in Escherichia coli BL21 after 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50436057(CHEMBL2397072)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to human beta-catenin expressed in Escherichia coli BL21 after 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50436056(CHEMBL2397073)
Affinity DataKd:  60nMAssay Description:Binding affinity to human beta-catenin expressed in Escherichia coli BL21 after 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50246103(CHEMBL4080446)
Affinity DataKd:  103nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed