TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin
Curated by ChEMBL
Humboldt Universit£T Zu Berlin
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Displacement of fluorescent H-Abu-Arg-Pro-Phe-Lys-NH-FAM-NH2 peptide from XIAP BIR3 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin
Curated by ChEMBL
Humboldt Universit£T Zu Berlin
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Displacement of fluorescent H-Abu-Arg-Pro-Phe-Lys-NH-FAM-NH2 peptide from XIAP BIR3 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin
Curated by ChEMBL
Humboldt Universit£T Zu Berlin
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Displacement of fluorescent H-Abu-Arg-Pro-Phe-Lys-NH-FAM-NH2 peptide from XIAP BIR3 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Inhibition of TAMRA-labeled cRaf peptide binding to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of TAMRA-labeled cRaf peptide binding to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin
Curated by ChEMBL
Humboldt Universit£T Zu Berlin
Curated by ChEMBL
Affinity DataIC50: 1.52E+3nMAssay Description:Displacement of fluorescent H-Abu-Arg-Pro-Phe-Lys-NH-FAM-NH2 peptide from XIAP BIR3 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of TAMRA-labeled cRaf peptide binding to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of beta-catenin-mediated transcriptional activity in Wnt3a-stimulated human HeLa cells after 24 hrs by Dual-Glo luciferase reporter gene a...More data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of beta-catenin-mediated transcriptional activity in Wnt3a-stimulated human HeLa cells after 24 hrs by Dual-Glo luciferase reporter gene a...More data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of 14-3-3zeta (unknown origin) in human U87 cells assessed as decrease in exogenous 14-3-3zeta-induced MMP1 mRNA levels after 24 hrs by RT...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of His-tagged beta-catenin (134 to 668 residues)/CM-5 sensor chip immobilized N-terminal GST-tagged TCF4 interaction (unknown origin) prei...More data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 1.30E+4nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 99nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 38nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 91nMAssay Description:Binding affinity to full-length beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociation c...More data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 6.40E+3nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 59nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: >2.00E+4nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 13nMAssay Description:Binding affinity to human beta-catenin (134 to 665 residues) expressed in Escherichia coli BL21 assessed as dissociation constant incubated for 45 mi...More data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 53nMAssay Description:Binding affinity to human beta-catenin (134 to 665 residues) expressed in Escherichia coli BL21 assessed as dissociation constant incubated for 45 mi...More data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 123nMAssay Description:Binding affinity to full-length recombinant beta-catenin (unknown origin) assessed as dissociation constant by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 5nMAssay Description:Binding affinity to human beta-catenin (129 to 780 residues) expressed in Escherichia coli Rosetta blue assessed as dissociation constant using fluor...More data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 5nMAssay Description:Binding affinity to human beta-catenin (129 to 780 residues) expressed in Escherichia coli Rosetta blue assessed as dissociation constant using fluor...More data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 450nMAssay Description:Binding affinity to beta-catenin (134 to 671 residues) (unknown origin) expressed in Escherichia coli BL21 assessed as dissociation constant by isoth...More data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 530nMAssay Description:Binding affinity to human beta-catenin (138 to 686 residues) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 420nMAssay Description:Binding affinity to beta-catenin (unknown origin) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 5.80E+5nMAssay Description:Binding affinity to CM-5 sensor chip immobilized His-tagged beta-catenin (134 to 668 residues) (unknown origin) expressed in Escherichia coli BL21 as...More data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 156nMAssay Description:Binding affinity to full-length beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociation c...More data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 9.00E+3nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: >2.00E+4nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: >2.00E+4nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 350nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 5.90E+3nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 510nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 450nMAssay Description:Inhibition of Tcf4 binding to beta-catenin (unknown origin)More data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 13nMAssay Description:Binding affinity to human beta-catenin expressed in Escherichia coli BL21 after 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 53nMAssay Description:Binding affinity to human beta-catenin expressed in Escherichia coli BL21 after 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 5.00E+3nMAssay Description:Binding affinity to human beta-catenin expressed in Escherichia coli BL21 after 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCatenin beta-1(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 60nMAssay Description:Binding affinity to human beta-catenin expressed in Escherichia coli BL21 after 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Target14-3-3 protein zeta/delta(Homo sapiens)
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataKd: 103nMAssay Description:Binding affinity to 14-3-3zeta (1 to 230 residues) (unknown origin) after 1 hr using FITC labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair