Affinity DataKi: 0.0600nMAssay Description:Inhibitory constant of the compound against human thrombin was determined in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibitory constant of the compound against human thrombin was determined in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibitory constant of the compound against human thrombin was determined in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibitory constant of the compound against human thrombin was determined in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Compound was evaluated for its inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Compound was tested for inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibitory constant of the compound against human thrombin was determined in vitro.More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Binding affinity to PPARgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Compound was evaluated for its inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibitory constant of the compound against human thrombin was determined in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Compound was evaluated for its inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibitory constant of the compound against human thrombin was determined in vitro.More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 0.820nMAssay Description:Binding affinity to PPARdelta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Compound was evaluated for its inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibitory constant of the compound against human thrombin was determined in vitro.More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity to PPARgamma (unknown origin) assessed as inhibition constant by Lanthascreen TR-FRET assay relative to controlMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibitory effect against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to PPARalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibitory effect against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibitory constant of the compound against human thrombin was determined in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibitory constant of the compound against human thrombin was determined in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Compound was evaluated for its inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Inhibitory constant of the compound against human thrombin was determined in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Inhibitory effect against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Compound was evaluated for its inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibitory effect against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibitory effect against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibitory effect against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Inhibitory effect against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 91nMAssay Description:Compound was evaluated for its inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 120nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataKi: 130nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: 134nMAssay Description:Compound was evaluated for its inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Compound was evaluated for its inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 152nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 153nMAssay Description:Compound was evaluated for its inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1 [I75L,S82A,Q83P,R149H,A150R,S151A](Homo sapiens (Human))
University Of Michigan
University Of Michigan
Affinity DataKi: 180nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: 200nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Binding affinity to PPARgamma (unknown origin) assessed as inhibition constant by Lanthascreen TR-FRET assay relative to controlMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair