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Found 47 with Last Name = 'jordan' and Initial = 'jb'
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172100(CHEMBL3809870)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human recombinant BACE1 expressed in HEK293 cells using peptide sequence EVNLAAEF as substrate preincubated for 60 mins followed by sub...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172104(CHEMBL3808441)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant BACE1 expressed in HEK293 cells using peptide sequence EVNLAAEF as substrate preincubated for 60 mins followed by sub...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172106(CHEMBL3809897)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant BACE1 expressed in HEK293 cells using peptide sequence EVNLAAEF as substrate preincubated for 60 mins followed by sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172100(CHEMBL3809870)
Affinity DataIC50:  16nMAssay Description:Inhibition of BACE1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172105(CHEMBL3808967)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant BACE1 expressed in HEK293 cells using peptide sequence EVNLAAEF as substrate preincubated for 60 mins followed by sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172106(CHEMBL3809897)
Affinity DataIC50:  58nMAssay Description:Inhibition of Cathepsin D (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50351920(CHEMBL1821811)
Affinity DataIC50:  74nMAssay Description:Inhibition of human recombinant BACE1 incubated for 60 mins prior to substrate addition measured after 60 mins by FRET assayMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172104(CHEMBL3808441)
Affinity DataIC50:  99nMAssay Description:Inhibition of Cathepsin D (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172104(CHEMBL3808441)
Affinity DataIC50:  191nMAssay Description:Inhibition of BACE1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172105(CHEMBL3808967)
Affinity DataIC50:  197nMAssay Description:Inhibition of Cathepsin D (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172106(CHEMBL3809897)
Affinity DataIC50:  458nMAssay Description:Inhibition of BACE1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172103(CHEMBL3808672)
Affinity DataIC50:  510nMAssay Description:Inhibition of Cathepsin D (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172101(CHEMBL3808988)
Affinity DataIC50:  820nMAssay Description:Inhibition of Cathepsin D (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172105(CHEMBL3808967)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of BACE1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172100(CHEMBL3809870)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Cathepsin D (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50351914(CHEMBL1821803)
Affinity DataIC50:  1.08E+5nMAssay Description:Inhibition of Cathepsin D (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172102(CHEMBL3809662)
Affinity DataIC50:  4.70E+5nMAssay Description:Inhibition of Cathepsin D (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379202(CHEMBL1981917)
Affinity DataKd:  3.25E+5nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379204(4-Methylquinolin-2-amine | CHEMBL2011275)
Affinity DataKd:  1.30E+6nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50351913(CHEMBL1821802)
Affinity DataKd:  3.40E+4nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50351914(CHEMBL1821803)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379200(CHEMBL2011272)
Affinity DataKd: >2.00E+6nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379206(CHEMBL2011278)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to BACE1 by NMR-based differential chemical shift perturbation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379199(CHEMBL2011271)
Affinity DataKd:  3.50E+5nMAssay Description:Binding affinity to BACE1 by NMR-based differential chemical shift perturbation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50154583(6-Methyl-quinolin-2-ylamine | CHEMBL361660)
Affinity DataKd:  1.60E+6nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM14322(2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL6123...)
Affinity DataKd:  9.00E+5nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379203(CHEMBL2011279)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to BACE1 by NMR-based differential chemical shift perturbation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379198(CHEMBL2011277)
Affinity DataKd:  3.90E+4nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379206(CHEMBL2011278)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379201(CHEMBL2011273)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to BACE1 by NMR-based differential chemical shift perturbation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50154584(6-Fluoro-quinolin-2-ylamine | CHEMBL185917)
Affinity DataKd:  1.28E+6nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172103(CHEMBL3808672)
Affinity DataKd:  140nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172104(CHEMBL3808441)
Affinity DataKd:  8nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172105(CHEMBL3808967)
Affinity DataKd:  25nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172106(CHEMBL3809897)
Affinity DataKd:  11nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172100(CHEMBL3809870)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50351914(CHEMBL1821803)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM64871(N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...)
Affinity DataKd:  1.14E+5nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172102(CHEMBL3809662)
Affinity DataKd:  0.600nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50172101(CHEMBL3808988)
Affinity DataKd:  16nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379200(CHEMBL2011272)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to BACE1 by NMR-based differential chemical shift perturbation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379199(CHEMBL2011271)
Affinity DataKd:  3.00E+5nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379205(CHEMBL2011276)
Affinity DataKd:  2.90E+6nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379201(CHEMBL2011273)
Affinity DataKd: >2.00E+6nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379202(CHEMBL1981917)
Affinity DataKd:  4.00E+5nMAssay Description:Binding affinity to BACE1 by NMR-based differential chemical shift perturbation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50154584(6-Fluoro-quinolin-2-ylamine | CHEMBL185917)
Affinity DataKd:  1.00E+6nMAssay Description:Binding affinity to BACE1 by NMR-based differential chemical shift perturbation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379207(CHEMBL2011274)
Affinity DataKd:  3.90E+6nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed