Affinity DataKi: 3.19E+3nMAssay Description:Competitive inhibition of human recombinant Tdp1 after 1 hr by FRET assayMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Francisella tularensis subsp. tularensis (strain S...)
Naval Research Laboratories
Curated by ChEMBL
Naval Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.40E+3nMAssay Description:Competitive inhibition of C-terminal His6-tagged Francisella tularensis SCHU S4 FabI expressed in Escherichia coli BL21 (DE3) using CrCoA as substrat...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Francisella tularensis subsp. tularensis (strain S...)
Naval Research Laboratories
Curated by ChEMBL
Naval Research Laboratories
Curated by ChEMBL
Affinity DataKi: 7.00E+3nMAssay Description:Competitive inhibition of C-terminal His6-tagged Francisella tularensis SCHU S4 FabI expressed in Escherichia coli BL21 (DE3) using CrCoA as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity by gel-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of strand transfer activity of recombinant HIV1 integrase using 5'-end-labeled 21-mer double-stranded DNA as substrate after 60 mins by el...More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of strand transfer activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity by high throughput electrochemiluminescent assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of strand transfer activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of MnCl2More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant HIV-1 integrase stand transfer activity expressed in Escherichia coli BL21(DE3) cells using 32P-labeled DNA substrate after...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of HIV-1 integrase-mediated strand transfer activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of strand transfer activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of MgCl2 by plate-based electrochemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity by high throughput electrochemiluminescent assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of strand transfer activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of HIV-1 integrase-mediated strand transfer activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of MgCl2 by gel-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity by gel-based assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of strand transfer activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity by high throughput electrochemiluminescent assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity by high throughput electrochemiluminescent assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of strand transfer activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity by gel-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity by high throughput electrochemiluminescent assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity by gel-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity by gel-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMpH: 7.5Assay Description:Ten-million cells (1 x 107), either human, chicken DT40 wild type, or knockout for TDP2 and complemented with human TDP2, were collected, washed, and...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of strand transfer activity of recombinant HIV1 integrase using 5'-end-labeled 21-mer double-stranded DNA as substrate after 60 mins by el...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of HIV-1 integrase-mediated strand transfer activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV1 integrase strand transfer activity by gel-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of strand transfer activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity by high throughput electrochemiluminescent assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity by high throughput electrochemiluminescent assay in presence of magnesiumMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2 [E242G,S244A,Q278R,I281T,K282R,R316G,P318T,Y321CH323L](Mus musculus (Mouse))
National Institutes Of Health
National Institutes Of Health
Affinity DataIC50: 29nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity by high throughput electrochemiluminescent assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of strand transfer activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in ...More data for this Ligand-Target Pair