Found 62 with Last Name = 'mccloskey' and Initial = 'l' 
Affinity DataKi: 60nMAssay Description:Inhibition of Escherichia coli PDFMore data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of Staphylococcus aureus PDF by absorbance detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibition of Staphylococcus aureus PDF by fluorescence detection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 500nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human ERG by QPatch assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human ERG by QPatch assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human ERG by QPatch assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human NaV1.5 expressed in HEK293 cells assessed as decrease in sodium current amplitude at -120 mV holding potential by Qpatch assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human NaV1.5 expressed in HEK293 cells assessed as decrease in sodium current amplitude at -120 mV holding potential by Qpatch assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human NaV1.5 expressed in HEK293 cells assessed as decrease in sodium current amplitude at -120 mV holding potential by Qpatch assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human ERG by QPatch assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human NaV1.5 expressed in HEK293 cells assessed as decrease in sodium current amplitude at -120 mV holding potential by Qpatch assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
TargetDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)(Klebsiella pneumoniae)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of hexa-histidine tagged Klebsiella pneumoniae UppS expressed in Escherichia coli assessed as reduction in IPP condensation to growing pre...More data for this Ligand-Target Pair
