Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]prazosin from human alpha1A adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]prazosin from human Alpha-1D adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.135nMAssay Description:Compound was tested for binding affinity against human hippocampus Alpha-1B adrenergic receptor using radioligand ([3H]-prazosin) binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.141nMAssay Description:Compound was tested for binding affinity against native Alpha-1B adrenergic receptor from rat liver using radioligand ([3H]prazosin) binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]prazosin from human Alpha-1D adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]prazosin from human Alpha-1D adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.209nMAssay Description:Compound was tested for binding affinity against native Alpha-1B adrenergic receptor from rat liver using radioligand ([3H]prazosin) binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.224nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1D adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
Affinity DataKi: 0.245nMAssay Description:Displacement of [3H]prazosin from human Alpha-1D adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.269nMAssay Description:Compound was tested for binding affinity against native Alpha-1B adrenergic receptor from rat liver using radioligand ([3H]prazosin) binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Pisa
Curated by PDSP Ki Database
University Of Pisa
Curated by PDSP Ki Database
Affinity DataKi: 0.300nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Pisa
Curated by PDSP Ki Database
University Of Pisa
Curated by PDSP Ki Database
Affinity DataKi: 0.302nMAssay Description:Displacement of [3H]N-methylscopolamine chloride from human cloned muscarinic M2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.309nMAssay Description:Compound was tested for binding affinity against cloned Alpha-1B adrenergic receptor from hamster smooth muscle using radioligand ([3H]prazosin) bind...More data for this Ligand-Target Pair
Affinity DataKi: 0.324nMAssay Description:Displacement of [3H]prazosin from human Alpha-1D adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.324nMAssay Description:Displacement of [3H]prazosin from human Alpha-1B adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.339nMAssay Description:Displacement of [3H]prazosin from human alpha1A adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.347nMAssay Description:Displacement of [3H]prazosin from human alpha1A adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Binding affinity of the compound towards Alpha-1A adrenergic receptor in bovine brainusing [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.363nMAssay Description:Compound was tested for binding Alpha-1B adrenergic receptor from rat liver using radioligand ([3H]prazosin) binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Binding affinity of the compound towards Alpha-1A adrenergic receptor in bovine brainusing [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Compound was tested for inhibiting [3H]pirenzepine Binding to Muscarinic receptor (M1) receptor in Rat Cortex HomogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Compound was tested for inhibiting [3H]pirenzepine Binding to Muscarinic receptor (M1) receptor in Rat Cortex HomogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 0.407nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1B adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
Affinity DataKi: 0.417nMAssay Description:Displacement of [3H]prazosin from human Alpha-1B adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.427nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1A adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
Affinity DataKi: 0.427nMAssay Description:Displacement of [3H]prazosin from human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.457nMAssay Description:Compound was tested for binding affinity against cloned Alpha-1B adrenergic receptor from hamster smooth muscle using radioligand ([3H]prazosin) bind...More data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]prazosin from human Alpha-1D adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity for rat cortex Muscarinic acetylcholine receptor M1Checked by AuthorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.513nMAssay Description:Displacement of [3H]prazosin from human cloned Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.513nMAssay Description:Evaluation of antagonistic affinity against muscarinic receptor (M2) in guinea pig left atriaMore data for this Ligand-Target Pair
Affinity DataKi: 0.513nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1D adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
Affinity DataKi: 0.525nMAssay Description:Compound was tested for binding affinity against cloned Alpha-1D adrenergic receptor from rat brain.More data for this Ligand-Target Pair
Affinity DataKi: 0.537nMAssay Description:Displacement of [3H]prazosin from human alpha1A adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.560nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 0.562nMAssay Description:Binding affinity against native Alpha-1 adrenergic receptor from rat cerebral cortex using radioligand [3H]-prazosin binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.575nMAssay Description:Compound was tested for binding affinity against native Dopamine receptor D2 from rat striatum using radioligand [3H]-spiperone)More data for this Ligand-Target Pair
Affinity DataKi: 0.575nMAssay Description:Compound was tested for binding affinity against cloned Alpha-1D adrenergic receptor from rat brain.More data for this Ligand-Target Pair
Affinity DataKi: 0.589nMAssay Description:Compound was tested for inhibiting [3H]pirenzepine Binding to Muscarinic receptor (M1) receptor in Rat Cortex HomogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 0.589nMAssay Description:Compound was tested for binding affinity against cloned Alpha-1B adrenergic receptor from hamster smooth muscle using radioligand ([3H]prazosin) bind...More data for this Ligand-Target Pair
Affinity DataKi: 0.589nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1A adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
Affinity DataKi: 0.603nMAssay Description:Displacement of [3H]prazosin from human alpha1A adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair