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Found 51 with Last Name = 'pedersen' and Initial = 'ds'
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandPNGBDBM161472(US9108978, 2.02)
Affinity DataKi:  30nM ΔG°:  -44.7kJ/mole IC50:  203nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandPNGBDBM161468(US9108978, 6.09)
Affinity DataKi:  90nM ΔG°:  -41.8kJ/mole IC50:  530nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161472(US9108978, 2.02)
Affinity DataKi:  225nM ΔG°:  -39.5kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161472(US9108978, 2.02)
Affinity DataKi:  420nM ΔG°:  -37.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandPNGBDBM161470(US9108978, 4.01)
Affinity DataKi:  660nM ΔG°:  -36.7kJ/mole IC50:  4.00E+3nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandPNGBDBM161469(US9108978, 6.07)
Affinity DataKi:  1.17E+3nM ΔG°:  -35.2kJ/mole IC50:  7.00E+3nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandPNGBDBM161467(US9108978, 3.25)
Affinity DataKi:  1.83E+3nM ΔG°:  -34.1kJ/mole IC50:  1.16E+4nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandPNGBDBM161471(US9108978, 6.34)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/mole IC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161470(US9108978, 4.01)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161469(US9108978, 6.07)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161468(US9108978, 6.09)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161470(US9108978, 4.01)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161469(US9108978, 6.07)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161468(US9108978, 6.09)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161467(US9108978, 3.25)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161467(US9108978, 3.25)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359672(CHEMBL1929262)
Affinity DataIC50:  5.14E+3nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359675(CHEMBL1929264)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359680(CHEMBL1929269)
Affinity DataIC50:  2.16E+4nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359683(CHEMBL1929272)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359674(CHEMBL1929263)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359682(CHEMBL1929271)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326793((+/-)(1S,2S,3R)-2-[(S)-Amino(carboxy)methyl]-3-cyc...)
Affinity DataIC50:  6.20E+4nMAssay Description:Antagonist activity at mGlu2 receptor expressed in CHO cells assessed as increase of cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359681(CHEMBL1929270)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50092271((Z)-5-Benzylidene-2-thioxothiazolidin-4-one | (Z)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359686(CHEMBL85105)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359685(CHEMBL1929274)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359684(CHEMBL1929273)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359679(CHEMBL1929268)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359678(CHEMBL1929267)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359677(CHEMBL1929266)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359676(CHEMBL1929265)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50359673(CHEMBL338214)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50331747((S)-2-amino-3-(1-((S)-1-carboxy-2-phenylethyl)-1H-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity at mGluR4 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326793((+/-)(1S,2S,3R)-2-[(S)-Amino(carboxy)methyl]-3-cyc...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu4 receptor expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326794((+/-)(1R,2S,3S)-3-[(S)-amino(carboxy)-methyl]-1,10...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu4 receptor expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326794((+/-)(1R,2S,3S)-3-[(S)-amino(carboxy)-methyl]-1,10...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu1 receptor expressed in CHO cells assessed as myo-[2-3H]Inositol turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50138781((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-methyl-c...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu4 receptor expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326794((+/-)(1R,2S,3S)-3-[(S)-amino(carboxy)-methyl]-1,10...)
Affinity DataEC50: >50nMAssay Description:Agonist activity at mGlu2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50138781((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-methyl-c...)
Affinity DataEC50: >10nMAssay Description:Agonist activity at mGlu2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50138781((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-methyl-c...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu1 receptor expressed in CHO cells assessed as myo-[2-3H]Inositol turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326793((+/-)(1S,2S,3R)-2-[(S)-Amino(carboxy)methyl]-3-cyc...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu1 receptor expressed in CHO cells assessed as myo-[2-3H]Inositol turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50331746((S)-2-amino-3-(1-(carboxymethyl)-1H-1,2,3-triazol-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity at mGluR4 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50331745((S)-2-amino-3-(1-((S)-1-carboxy-2-phenylethyl)-1H-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity at mGluR4 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50331744((S)-1-(2-amino-2-carboxyethyl)-1H-1,2,3-triazole-4...)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity at mGluR4 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50331748((S)-2-amino-3-(1-(carboxymethyl)-1H-1,2,3-triazol-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity at mGluR2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50331747((S)-2-amino-3-(1-((S)-1-carboxy-2-phenylethyl)-1H-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity at mGluR2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50331746((S)-2-amino-3-(1-(carboxymethyl)-1H-1,2,3-triazol-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity at mGluR2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50331745((S)-2-amino-3-(1-((S)-1-carboxy-2-phenylethyl)-1H-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity at mGluR2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50331744((S)-1-(2-amino-2-carboxyethyl)-1H-1,2,3-triazole-4...)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity at mGluR2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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