Compile Data Set for Download or QSAR
maximum 50k data
Found 369 with Last Name = 'rose' and Initial = 'cr'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176407(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2-diflu...)
Affinity DataKi:  0.100nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176411(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2,2-tri...)
Affinity DataKi:  0.100nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176407(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2-diflu...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176411(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2,2-tri...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50120502(2-Amino-N-[(R)-2-(3a-benzyl-2-tert-butyl-3-oxo-2,3...)
Affinity DataKi:  0.340nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50120504(2-Amino-N-[(R)-2-[3a-benzyl-3-oxo-2-(2,2,2-trifluo...)
Affinity DataKi:  0.450nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176403(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2-diflu...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM29061(CHEMBL201602 | pyrazolopyrimidinone-based antagoni...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM29061(CHEMBL201602 | pyrazolopyrimidinone-based antagoni...)
Affinity DataKi:  1nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176403(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2-diflu...)
Affinity DataKi:  1nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176402(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2,2-tri...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176402(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2,2-tri...)
Affinity DataKi:  1nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  1nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342721(CHEMBL1771259 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176418(8-(2-chlorophenyl)-9-(4-chlorophenyl)-1-(2,2,2-tri...)
Affinity DataKi:  1nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176418(8-(2-chlorophenyl)-9-(4-chlorophenyl)-1-(2,2,2-tri...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176416(2-(2-chlorophenyl)-3-(4-chlorophenyl)-5-ethyl-6-(2...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176415(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(3,3,3-tri...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176413(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-propyl-2H-...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176413(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-propyl-2H-...)
Affinity DataKi:  2nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176410(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2-fluoroe...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176416(2-(2-chlorophenyl)-3-(4-chlorophenyl)-5-ethyl-6-(2...)
Affinity DataKi:  3nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342728(CHEMBL1771260 | N1-(3-(2,6-dichloro-4-ethoxyphenyl...)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342721(CHEMBL1771259 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [125]sauvagin from rat recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176415(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(3,3,3-tri...)
Affinity DataKi:  4nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176409(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-ethyl-2H-p...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176412(6-benzyl-2-(2-chlorophenyl)-3-(4-chlorophenyl)-2H-...)
Affinity DataKi:  4nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176404(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2,2-tri...)
Affinity DataKi:  4nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176409(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-ethyl-2H-p...)
Affinity DataKi:  4nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342726(CHEMBL1771262 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50120505(2-Amino-N-{(R)-1-(2,4-difluoro-benzyloxymethyl)-2-...)
Affinity DataKi:  5nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176410(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2-fluoroe...)
Affinity DataKi:  5nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176412(6-benzyl-2-(2-chlorophenyl)-3-(4-chlorophenyl)-2H-...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342724(CHEMBL1771264 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176414(2-(2-chlorophenyl)-3-(4-chlorophenyl)-5-isopropyl-...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342729(CHEMBL1771258 | N1-(3-(2,6-dichlorophenyl)-2,5-dim...)
Affinity DataKi:  7nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50083974(2-Amino-N-[(R)-2-((R)-3a-benzyl-2-methyl-3-oxo-2,3...)
Affinity DataKi:  7nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386955(CHEMBL2048820)
Affinity DataKi:  7nMAssay Description:Antagonist activity at human GHS-R1a expressed in HEK293 cells assessed as inhibition of ghrelin-induced europium-labeled GTP binding by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176404(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2,2-tri...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342727(CHEMBL1771261 | N1-(3-(2,6-dichloro-4-propoxypheny...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386949(CHEMBL2048814)
Affinity DataKi:  11nMAssay Description:Antagonist activity at human GHS-R1a expressed in HEK293 cells assessed as inhibition of ghrelin-induced europium-labeled GTP binding by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176406(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(piperidin...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176414(2-(2-chlorophenyl)-3-(4-chlorophenyl)-5-isopropyl-...)
Affinity DataKi:  13nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386952(CHEMBL2048817)
Affinity DataKi:  14nMAssay Description:Antagonist activity at human GHS-R1a expressed in HEK293 cells assessed as inhibition of ghrelin-induced europium-labeled GTP binding by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386957(CHEMBL2048822)
Affinity DataKi:  14nMAssay Description:Antagonist activity at human GHS-R1a expressed in HEK293 cells assessed as inhibition of ghrelin-induced europium-labeled GTP binding by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386948(CHEMBL2048813)
Affinity DataKi:  14nMAssay Description:Antagonist activity at human GHS-R1a expressed in HEK293 cells assessed as inhibition of ghrelin-induced europium-labeled GTP binding by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386953(CHEMBL2048818)
Affinity DataKi:  17nMAssay Description:Antagonist activity at human GHS-R1a expressed in HEK293 cells assessed as inhibition of ghrelin-induced europium-labeled GTP binding by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50120503(2-Amino-N-[(R)-2-(3a-benzyl-2-methyl-3-oxo-2,3,3a,...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176417(2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-cyclohexyl...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 369 total ) | Next | Last >>
Jump to: