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Found 35 with Last Name = 'sgobba' and Initial = 'm'
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16315(6-[(5-chloro-3-methyl-1-benzofuran-2-)sulfonyl]-2,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50009767(2-(4-oxo-3-((6-(trifluoromethyl)benzo[d]thiazol-2-...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16469(2-{3-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methy...)
Affinity DataIC50:  5nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16239(2-(5-chloro-2-{[(3-nitrophenyl)methyl]carbamoyl}ph...)
Affinity DataIC50:  6nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50222613(2-(2-((3-nitrobenzyl)carbamoyl)-4-cyano-5-fluoroph...)
Affinity DataIC50:  7nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50222611(2-(5-fluoro-2-(((4,5,7-trifluorobenzo[d]thiazol-2-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50067407((3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[p...)
Affinity DataIC50:  15nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16457(6-[(5-chloro-1-benzofuran-2-)sulfonyl]-2,3-dihydro...)
Affinity DataIC50:  25nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50222614(2-(5-fluoro-2-(((5-(trifluoromethyl)benzo[d]thiazo...)
Affinity DataIC50:  29nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16313(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamothioy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16512((2S,4S)-6-fluoro-2',5'-dioxo-2,3-dihydrospiro[1-be...)
Affinity DataIC50:  35nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50222609(2-(5-chloro-2-(((5-(trifluoromethyl)benzo[d]thiazo...)
Affinity DataIC50:  35nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16496(2-{3-[(4-bromo-2-fluorophenyl)methyl]-7-chloro-2,4...)
Affinity DataIC50:  44nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50009777((ponalrestat)[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,...)
Affinity DataIC50:  56.5nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50038843((4R)-2-(4-bromo-2-fluorobenzyl)-6-fluoro-1H,2'H,5'...)
Affinity DataIC50:  73nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16631(6-[(5,7-dichloro-1-benzofuran-2-)sulfonyl]-2,3-dih...)
Affinity DataIC50:  87nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50222612(2-(2,6-dimethyl-4-(2-o-tolylacetamido)phenylsulfon...)
Affinity DataIC50:  108nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16456(6-(1-benzofuran-2-sulfonyl)-2,3-dihydropyridazin-3...)
Affinity DataIC50:  150nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50222610(2-(2-((4-bromo-2-fluorobenzyl)carbamoyl)phenoxy)ac...)
Affinity DataIC50:  176nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50067397((3S)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[p...)
Affinity DataIC50:  190nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16630(6-[(5-methoxy-1-benzofuran-2-)sulfonyl]-2,3-dihydr...)
Affinity DataIC50:  230nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089423((2R,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-...)
Affinity DataIC50:  570nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16623(6-[(5-chloro-1H-indole-2-)sulfonyl]-2,3-dihydropyr...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16426(2-(2-hydroxyphenyl)acetic acid | 2-Hydroxyphenylac...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16429(2,6-Dichlorophenylacetic acid | 2-(2,6-dichlorophe...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM34571(6,7-bis(oxidanyl)chromen-2-one | 6,7-dihydroxy-1-b...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16433(CHEMBL14184 | Caproic acid | Hexanoic acid | n-Cap...)
Affinity DataIC50:  6.82E+4nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16419(2-phenylacetic acid | Benzeneacetic acid | CHEMBL1...)
Affinity DataIC50:  9.60E+4nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50206007(3-Hydroxy-chromen-2-one | 3-hydroxy-2H-chromen-2-o...)
Affinity DataIC50:  1.31E+5nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50206008(6-hydroxy-7-methoxy-2H-chromen-2-one | CHEMBL39032...)
Affinity DataIC50:  1.38E+5nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50055710(4-HYDROXY-2H-CHROMEN-2-ONE | 4-Hydroxy-chromen-2-o...)
Affinity DataIC50:  1.95E+5nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50174558(7-hydroxy-2H-1-benzopyran-2-one | 7-hydroxy-2H-chr...)
Affinity DataIC50:  2.36E+5nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50078820(6,7-Dihydroxy-4-methyl-chromen-2-one | 6,7-dihydro...)
Affinity DataIC50:  2.46E+5nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-Dihydroxy-2H-1-benzopyran-2-one | 7,8-dihydrox...)
Affinity DataIC50:  3.90E+5nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed