TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Competitive inhibition of PTP1B mediated pNPP hydrolysis by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 430nMAssay Description:Inhibitory constant of compound against Cell division cycle 25B was determined using mFP as a substrateMore data for this Ligand-Target Pair
Affinity DataKi: 640nMAssay Description:Inhibitory constant of compound against Cell division cycle 25 was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 640nMAssay Description:Inhibitory constant of compound against Cell division cycle 25B was determined using mFP as a substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of human recombinant PTP1B by Lineweaver-Burke plotMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Inhibitory constant of compound against Cdc25B phosphatase was determined using mFP as a substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00200nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.00500nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0390nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0670nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0760nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.103nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.134nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.164nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.182nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.226nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.229nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.267nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.362nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.375nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.421nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.454nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
TargetPeptide deformylase(Staphylococcus aureus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Staphylococcus aureus peptide deformylase using N-formylmethionine-alanine-serine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalpha by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University
Curated by ChEMBL
Kyung Hee University
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of T type calcium channel Cav3.1 (unknown origin) expressed in HEK293T cells by patch clamp method relative to controlMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University
Curated by ChEMBL
Kyung Hee University
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of T type calcium channel Cav3.1 (unknown origin) expressed in HEK293T cells by patch clamp method relative to controlMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair