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Found 200 with Last Name = 'sohn' and Initial = 'j'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50311254(2-hydroxy-4-(2-hydroxy-6-pentadecyl-4-((2S,3R,4S,5...)
Affinity DataKi:  100nMAssay Description:Competitive inhibition of PTP1B mediated pNPP hydrolysis by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129580(3-[4,6-Dichloro-7-(3-methyl-but-2-enyl)-1H-indol-3...)
Affinity DataKi:  430nMAssay Description:Inhibitory constant of compound against Cell division cycle 25B was determined using mFP as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129576(2,5-Dihydroxy-3-[7-(3,7,11-trimethyl-dodeca-2,6,10...)
Affinity DataKi:  640nMAssay Description:Inhibitory constant of compound against Cell division cycle 25 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129574(2,5-Dihydroxy-3-[7-(3-methyl-but-2-enyl)-1H-indol-...)
Affinity DataKi:  640nMAssay Description:Inhibitory constant of compound against Cell division cycle 25B was determined using mFP as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50374277(CHEMBL403094)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human recombinant PTP1B by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibitory constant of compound against Cdc25B phosphatase was determined using mFP as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM198005(US9221790, 15)
Affinity DataIC50:  0.00200nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197995(US9221790, 5)
Affinity DataIC50:  0.00500nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197993(US9221790, 3)
Affinity DataIC50:  0.0390nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197997(US9221790, 7)
Affinity DataIC50:  0.0670nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM198000(US9221790, 10)
Affinity DataIC50:  0.0760nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197996(US9221790, 6)
Affinity DataIC50:  0.103nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM198003(US9221790, 13)
Affinity DataIC50:  0.134nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197992(US9221790, 2)
Affinity DataIC50:  0.164nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197998(US9221790, 8)
Affinity DataIC50:  0.182nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197991(US9221790, 1)
Affinity DataIC50:  0.226nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197994(US9221790, 4)
Affinity DataIC50:  0.229nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197999(US9221790, 9)
Affinity DataIC50:  0.267nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50005836(4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl...)
Affinity DataIC50:  0.362nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM198004(US9221790, 14)
Affinity DataIC50:  0.375nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM198002(US9221790, 12)
Affinity DataIC50:  0.421nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM198001(US9221790, 11)
Affinity DataIC50:  0.454nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptide deformylase(Staphylococcus aureus)
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50089194((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Staphylococcus aureus peptide deformylase using N-formylmethionine-alanine-serine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)

Curated by ChEMBL
LigandPNGBDBM13373((2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpro...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477454(CHEMBL245688)
Affinity DataIC50:  100nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50311254(2-hydroxy-4-(2-hydroxy-6-pentadecyl-4-((2S,3R,4S,5...)
Affinity DataIC50:  190nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50311256(4-(2,4-dihydroxy-6-pentadecylbenzoyloxy)-2-hydroxy...)
Affinity DataIC50:  220nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477429(CHEMBL248132)
Affinity DataIC50:  300nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50309551(17alpha-(17-1,2,3-Triazolmethyl)ethynyl-estra-1,3,...)
Affinity DataIC50:  400nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalpha by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477447(CHEMBL248327)
Affinity DataIC50:  500nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477441(CHEMBL247674)
Affinity DataIC50:  500nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)

Curated by ChEMBL
LigandPNGBDBM50114333(3-Methyl-but-2-enoic acid 4-{(S)-2-[(S)-2-((R)-2-a...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50222222(CHEMBL394956 | KYS-05090 | N-benzyl-2-(3-(biphenyl...)
Affinity DataIC50:  510nMAssay Description:Inhibition of T type calcium channel Cav3.1 (unknown origin) expressed in HEK293T cells by patch clamp method relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50311254(2-hydroxy-4-(2-hydroxy-6-pentadecyl-4-((2S,3R,4S,5...)
Affinity DataIC50:  510nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50311257(2-hydroxy-6-pentadecyl-4-((2S,3R,4S,5S,6R)-3,4,5-t...)
Affinity DataIC50:  590nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477437(CHEMBL247930)
Affinity DataIC50:  600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477456(CHEMBL392878)
Affinity DataIC50:  600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50105462(CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...)
Affinity DataIC50:  600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477434(CHEMBL247931)
Affinity DataIC50:  600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477428(CHEMBL248131)
Affinity DataIC50:  700nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477439(CHEMBL247524)
Affinity DataIC50:  700nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477435(CHEMBL247328)
Affinity DataIC50:  800nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50067040(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)
Affinity DataIC50:  800nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477426(CHEMBL391205)
Affinity DataIC50:  800nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)

Curated by ChEMBL
LigandPNGBDBM50114334(3-Methyl-butyric acid 4-{(S)-2-[(S)-2-((R)-2-amino...)
Affinity DataIC50:  820nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)

Curated by ChEMBL
LigandPNGBDBM50114335(4-Chloro-benzoic acid (S)-2-[(S)-2-((R)-2-amino-3-...)
Affinity DataIC50:  820nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50294526(CHEMBL551842 | cid_73157 | lobaric acid)
Affinity DataIC50:  870nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50558021(CHEMBL4779125)
Affinity DataIC50:  890nMAssay Description:Inhibition of T type calcium channel Cav3.1 (unknown origin) expressed in HEK293T cells by patch clamp method relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477450(CHEMBL247725)
Affinity DataIC50:  900nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50477444(CHEMBL247927)
Affinity DataIC50:  900nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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