TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of zebra fish recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human TDP2More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant TPD1 (unknown origin) activity using 3'-phosphotyrosine-containing 5'-[32P]-labeled single-stranded DNA oligonucleotide by ...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of mouse recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of zebra fish recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of zebra fish recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human recombinant TPD2 activity using 5'phosphotyrosine-containing 19-mer single-stranded oligonucleotide DNA substrate by PAGE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of recombinant TPD1 (unknown origin) activity using 3'-phosphotyrosine-containing 5'-[32P]-labeled single-stranded DNA oligonucleotide by ...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant TPD1 (unknown origin) activity using 3'-phosphotyrosine-containing 5'-[32P]-labeled single-stranded DNA oligonucleotide by ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP1 using 5'-[32P]-labeled N14Y as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP1 using 5'-[32P]-labeled N14Y as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP1 using 5'-[32P]-labeled N14Y as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of mouse recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of mouse recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair