Affinity DataKi: 0.339nM ΔG°: -54.1kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 0.407nM ΔG°: -53.6kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -51.4kJ/mole EC50: 2nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.7kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity of compound for Dopamine receptor D2 using [3H]-N-0437More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:In vitro binding affinity of the compound towards Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.6kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity of compound for Dopamine receptor D1 using [3H]-SCH- 23390More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.9kJ/mole EC50: 16nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.9kJ/mole EC50: 8nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 6nM ΔG°: -46.9kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH4R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity of compound for Dopamine receptor D2 using [3H]-N-0437More data for this Ligand-Target Pair
Affinity DataKi: 6nM ΔG°: -46.9kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH4R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 8nM ΔG°: -46.2kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH4R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity of compound for Dopamine receptor D2 using [3H]-N-0437More data for this Ligand-Target Pair
Affinity DataKi: 32nM ΔG°: -42.8kJ/mole EC50: 79nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 33nM ΔG°: -42.7kJ/mole EC50: 200nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 40nM ΔG°: -42.2kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 41nM ΔG°: -42.2kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 56nM ΔG°: -41.4kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 89nM ΔG°: -40.2kJ/mole EC50: 79nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Binding affinity of compound for Dopamine receptor D1 using [3H]-SCH- 23390More data for this Ligand-Target Pair
Affinity DataKi: 155nM ΔG°: -38.9kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 162nM ΔG°: -38.8kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:In vitro binding affinity of the compound towards Dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataKi: 257nM ΔG°: -37.6kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 417nM ΔG°: -36.4kJ/mole EC50: 631nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 427nM ΔG°: -36.4kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Binding affinity of compound for Dopamine receptor D1 using [3H]-SCH- 23390More data for this Ligand-Target Pair
Affinity DataKi: 537nM ΔG°: -35.8kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 708nM ΔG°: -35.1kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 813nM ΔG°: -34.8kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 1.74E+3nM ΔG°: -32.9kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 2.23E+3nMAssay Description:In vitro binding affinity of the compound towards Dopamine receptor D2More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:In vitro binding affinity of the compound towards Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 2.51E+3nM ΔG°: -32.0kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 2.51E+3nM ΔG°: -32.0kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of the compound towards Dopamine receptor D2More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of GöTeborg
Curated by ChEMBL
University Of GöTeborg
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Binding affinity towards 5-HT2C receptor from rat using [3H]-mesulergine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Binding affinity towards human Dopamine receptor D2More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of GöTeborg
Curated by ChEMBL
University Of GöTeborg
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor from rat frontal cortex using [3H]-ketanserin as radioligandMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of GöTeborg
Curated by ChEMBL
University Of GöTeborg
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of binding of 1.0 nM [3H]-pirenzepine to cloned human Muscarinic acetylcholine receptor M1 expressed in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Binding affinity towards human D4.2 receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Binding affinity towards Dopamine receptor D2 of rat corpus striatum using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Binding affinity towards human Dopamine receptor D3More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of GöTeborg
Curated by ChEMBL
University Of GöTeborg
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibition of binding of 1.0 nM [3H]-pirenzepine to cloned human Muscarinic acetylcholine receptor M1 expressed in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Binding affinity towards human Dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Binding affinity towards D1 CNS receptor of rat corpus striatum using [3H]-SCH-23,390 as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of GöTeborg
Curated by ChEMBL
University Of GöTeborg
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Binding affinity towards 5-HT2C receptor from rat using [3H]-mesulergine as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of GöTeborg
Curated by ChEMBL
University Of GöTeborg
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor from rat frontal cortex using [3H]-ketanserin as radioligandMore data for this Ligand-Target Pair