BindingDB PrimarySearch

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508504(CHEMBL4547692)

IC50: 2.51E+3nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

14-3-3 protein sigma(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL

BDBM50462078(CHEMBL4243744)

IC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

14-3-3 protein sigma(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL

BDBM50462080(CHEMBL4250552)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

14-3-3 protein sigma(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL

BDBM50462083(CHEMBL4237531)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

14-3-3 protein sigma(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL

BDBM50462084(CHEMBL4247540)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

14-3-3 protein sigma(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL

BDBM50462085(CHEMBL4240436)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508476(CHEMBL4464674)

IC50: 3.98E+3nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508501(CHEMBL4529356)

IC50: 5.01E+3nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508484(CHEMBL4460396)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508471(CHEMBL4471804)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508464(CHEMBL4447969)

IC50: 6.31E+3nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508478(CHEMBL4572303)

IC50: 7.94E+3nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508439(CHEMBL4551719)

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

14-3-3 protein zeta/delta(Homo sapiens)
Eindhoven University Of Technology

Curated by ChEMBL

BDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)

IC50: 9.30E+3nMAssay Description:Binding affinity to GST-tagged 14-3-3-zeta (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with PRAS40...More data for this Ligand-Target Pair

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508511(CHEMBL4516926)

IC50: 1.00E+4nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508508(CHEMBL4540401)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508494(CHEMBL4519919)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508468(CHEMBL4463144)

IC50: 1.26E+4nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508451(CHEMBL4462411)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508447(CHEMBL4559284)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508450(CHEMBL4475357)

IC50: 1.58E+4nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508470(CHEMBL4473289)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508472(CHEMBL4462256)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508493(CHEMBL4554978)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508515(CHEMBL4448059)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

14-3-3 protein gamma(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL

BDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)

IC50: 1.64E+4nMAssay Description:Binding affinity to GST-tagged 14-3-3-gamma (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with PRAS4...More data for this Ligand-Target Pair

CHEMBL PC cid PC sid PDB Similars

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508429(CHEMBL4438829)

IC50: 2.00E+4nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508524(CHEMBL4535901)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508444(CHEMBL4516024)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508475(CHEMBL4451846)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508467(CHEMBL4474497)

IC50: 2.51E+4nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508502(CHEMBL4578004)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508491(CHEMBL4526962)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508495(CHEMBL4582012)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508499(CHEMBL4587100)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508438(CHEMBL4559787)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508480(CHEMBL4561862)

IC50: 3.16E+4nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508452(CHEMBL4575527)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508448(CHEMBL4570062)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508427(CHEMBL4573383)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508525(CHEMBL4473247)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508512(CHEMBL4552993)

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508510(CHEMBL4476374)

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Cyclin-dependent kinase 4(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL

BDBM50297259(1,2-Bis-(indol-1-yl)-ethane | CHEMBL549792)

IC50: 3.70E+4nMAssay Description:Inhibition of human CDK4/ Cyclin D1 catalytic subunit expressed in Sf9 insect cells assessed as GST-RB152 fusion protein phosphorylation-associated d...More data for this Ligand-Target Pair

CHEMBL PC cid PC sid Patents Similars

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Cyclin-dependent kinase 4(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL

BDBM50297274(1-(5-Methyl-2,3-dihydro-indol-1-yl)-2-(5-methyl-1H...)

IC50: 3.80E+4nMAssay Description:Inhibition of human CDK4/ Cyclin D1 catalytic subunit expressed in Sf9 insect cells assessed as GST-RB152 fusion protein phosphorylation-associated d...More data for this Ligand-Target Pair

CHEMBL PC cid PC sid Similars

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Cyclin-dependent kinase 4(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL

BDBM50297282(5-Chloro-3-[2-(5-chloro-3a,7a-dihydro-indol-1-yl)-...)

CHEMBL PC cid PC sid Similars

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Cyclin-dependent kinase 4(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL

BDBM50297260(1,3-Bis-(indol-1-yl)-propane | CHEMBL557456)

CHEMBL PC cid PC sid Similars

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508520(CHEMBL4457869)

IC50: 3.98E+4nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair

Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

BDBM50508523(CHEMBL4560441)