Affinity DataKi: 1.10nMAssay Description:Inhibition of recombinant His-tagged human cathepsin K expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Inhibition of recombinant His-tagged human cathepsin K expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 195nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 239nMAssay Description:Inhibition of recombinant human cathepsin S expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 406nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 735nMAssay Description:Inhibition of recombinant human cathepsin S expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 909nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 3.35E+3nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Compound tested for the inhibition of E. coli Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: <2nMAssay Description:Compound tested for the inhibition of E. coli Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant His-tagged human cathepsin K expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant His-tagged human cathepsin K expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Compound tested for the inhibition of human Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: >54nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair