Affinity DataKi: 0.300nMAssay Description:Inhibition of 6-His tagged recombinant human glyoxalase 1 transfected in Escherichia coli BL21 (DE3) assessed as S-D-lactoylglutathione formation by ...More data for this Ligand-Target Pair
Affinity DataKi: 0.960nMAssay Description:Competitive inhibition of human Glyoxalase-1 using GSH and MGO as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Competitive inhibition of human Glyoxalase-1 using GSH and MGO as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of 6-His tagged recombinant human glyoxalase 1 transfected in Escherichia coli BL21 (DE3) assessed as S-D-lactoylglutathione formation by ...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of human Glyoxalase-1 using GSH and MGO as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human erythrocyte Glyoxalase-1 using GSH and MGO as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Competitive inhibition of human Glyoxalase-1 using GSH and MGO as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human Glyoxalase-1More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human glyoxalase 1More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human erythrocyte Glyoxalase-1More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Competitive inhibition of human Glyoxalase-1 using GSH and MGO as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human erythrocyte Glyoxalase-1More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human glyoxalase 1More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human glyoxalase 1More data for this Ligand-Target Pair
TargetHydroxyacylglutathione hydrolase, mitochondrial(Bos taurus)
Chengdu University
Curated by ChEMBL
Chengdu University
Curated by ChEMBL
Affinity DataKi: 81nMAssay Description:Inhibition of bovine liver glyoxalase 2More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of human glyoxalase 1More data for this Ligand-Target Pair
TargetHydroxyacylglutathione hydrolase, mitochondrial(Bos taurus)
Chengdu University
Curated by ChEMBL
Chengdu University
Curated by ChEMBL
Affinity DataKi: 138nMAssay Description:Inhibition of bovine liver glyoxalase 2More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Competitive inhibition of recombinant mouse His-tagged Glyoxalase-1 using GSH and MGO as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of human erythrocyte Glyoxalase-1More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) using GSH and MGO as substrates preincubated with substrates for 6 mins followed by enzyme addition by sp...More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Competitive inhibition of recombinant mouse His-tagged Glyoxalase-1 using GSH and MGO as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Inhibition of recombinant mouse Glyoxalase-1 expressed in Escherichia coli BL21 (DE3) pLysS cells using GSH and MGO as substrate by Dixon plotMore data for this Ligand-Target Pair
Affinity DataKi: 330nMAssay Description:Inhibition of human glyoxalase 1More data for this Ligand-Target Pair
TargetHydroxyacylglutathione hydrolase, mitochondrial(Bos taurus)
Chengdu University
Curated by ChEMBL
Chengdu University
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of bovine liver glyoxalase 2More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 108nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 124nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 250nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 630nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 730nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.00E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.10E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.10E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.10E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.20E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.20E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.20E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.30E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.30E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.30E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.40E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.40E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair