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3 similar compounds to monomer 31046

Compile data set for download or QSAR
Wt: 354.4
BDBM50262181

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50262181   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM50262181
PNG
(CHEMBL4064879)
Show SMILES Cc1nnc2c(Nc3cccc(CNC(=O)OC(C)(C)C)c3)nccn12
Show InChI InChI=1S/C18H22N6O2/c1-12-22-23-16-15(19-8-9-24(12)16)21-14-7-5-6-13(10-14)11-20-17(25)26-18(2,3)4/h5-10H,11H2,1-4H3,(H,19,21)(H,20,25)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of BRD4 BD1-BD2 (unknown origin) using tetraacetylated histone peptide as substrate after 2 hrs by alphascreen assay


Bioorg Med Chem Lett 27: 4606-4613 (2017)


Article DOI: 10.1016/j.bmcl.2017.09.025
BindingDB Entry DOI: 10.7270/Q20R9RWC
More data for this
Ligand-Target Pair