BindingDB logo
myBDB logout

18 similar compounds to monomer 50091987

Compile data set for download or QSAR
Wt: 292.3
BDBM32635
Purchase
Wt: 277.3
BDBM46010
Purchase
Wt: 257.2
BDBM49228
Purchase
Wt: 321.3
BDBM75523
Purchase
Wt: 291.3
BDBM75513
Purchase
Wt: 277.3
BDBM76665
Purchase
Wt: 307.3
BDBM80521
Purchase
Wt: 263.2
BDBM95946
Purchase
Wt: 307.3
BDBM114920
Purchase
Wt: 295.2
BDBM50086683
Wt: 295.2
BDBM50086684
Wt: 297.7
BDBM50091999
Purchase
Wt: 297.7
BDBM50092002
Wt: 263.2
BDBM50091993
Purchase
Wt: 288.3
BDBM50091975
Displayed 1 to 15 (of 18 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 32635,46010,49228,75523,75513,76665,80521,95946,114920,50086683,50086684,50091999,50092002,50091993,50091975   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Major prion protein


(Ovis aries)
BDBM75523
PNG
(3-Methoxy-naphthalene-2-carboxylic acid (4-ethoxy-...)
Show SMILES CCOc1ccc(NC(=O)c2cc3ccccc3cc2OC)cc1
Show InChI InChI=1S/C20H19NO3/c1-3-24-17-10-8-16(9-11-17)21-20(22)18-12-14-6-4-5-7-15(14)13-19(18)23-2/h4-13H,3H2,1-2H3,(H,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 512n/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISA


ACS Med Chem Lett 4: 647-650 (2013)


Article DOI: 10.1021/ml300454k
BindingDB Entry DOI: 10.7270/Q26D5VCS
More data for this
Ligand-Target Pair
Calmodulin/Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50086684
PNG
(3,6-Dihydroxy-naphthalene-2-carboxylic acid (3-hyd...)
Show SMILES Oc1cccc(NC(=O)c2cc3ccc(O)cc3cc2O)c1
Show InChI InChI=1S/C17H13NO4/c19-13-3-1-2-12(9-13)18-17(22)15-7-10-4-5-14(20)6-11(10)8-16(15)21/h1-9,19-21H,(H,18,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Athenex Inc.

Curated by ChEMBL


Assay Description
Inhibition of full length human recombinant pp60c-src using RR-SRC as substrate


J Med Chem 61: 4704-4719 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00164
More data for this
Ligand-Target Pair
ATP-binding cassette sub-family G member 2


(Homo sapiens (Human))
BDBM32635
PNG
(NSC306698)
Show SMILES Cc1ccc(NC(=[OH+])c2cc3ccccc3cc2O)c(C)c1
Show InChI InChI=1S/C19H17NO2/c1-12-7-8-17(13(2)9-12)20-19(22)16-10-14-5-3-4-6-15(14)11-18(16)21/h3-11,21H,1-2H3,(H,20,22)/p+1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.40E+3n/an/an/an/a7.437



SAIC-Frederick



Assay Description
IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...


Mol Cancer Ther 6: 3271-8 (2007)


Article DOI: 10.1158/1535-7163.MCT-07-0352
BindingDB Entry DOI: 10.7270/Q21C1V7K
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens (Human))
BDBM46010
PNG
(2-methoxy-N-(2-naphthalenyl)benzamide | 2-methoxy-...)
Show SMILES COc1ccccc1C(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C18H15NO2/c1-21-17-9-5-4-8-16(17)18(20)19-15-11-10-13-6-2-3-7-14(13)12-15/h2-12H,1H3,(H,19,20)
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2CR5RRG
More data for this
Ligand-Target Pair
Nuclear factor NF-kappa-B


(Homo sapiens (Human))
BDBM49228
PNG
(2-hydroxy-N-p-phenetyl-benzamide | MLS000053964 | ...)
Show SMILES CCOc1ccc(NC(=O)c2ccccc2O)cc1
Show InChI InChI=1S/C15H15NO3/c1-2-19-12-9-7-11(8-10-12)16-15(18)13-5-3-4-6-14(13)17/h3-10,17H,2H2,1H3,(H,16,18)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 9.07E+6n/an/an/an/a



SRMLSC

Curated by PubChem BioAssay


Assay Description
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q27P8WT7
More data for this
Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2


(Homo sapiens (Human))
BDBM75513
PNG
(3-methoxy-N-(4-methylphenyl)-2-naphthalenecarboxam...)
Show SMILES COc1cc2ccccc2cc1C(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C19H17NO2/c1-13-7-9-16(10-8-13)20-19(21)17-11-14-5-3-4-6-15(14)12-18(17)22-2/h3-12H,1-2H3,(H,20,21)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a>1.16E+5n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2Q23XQJ
More data for this
Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2


(Homo sapiens (Human))
BDBM75523
PNG
(3-Methoxy-naphthalene-2-carboxylic acid (4-ethoxy-...)
Show SMILES CCOc1ccc(NC(=O)c2cc3ccccc3cc2OC)cc1
Show InChI InChI=1S/C20H19NO3/c1-3-24-17-10-8-16(9-11-17)21-20(22)18-12-14-6-4-5-7-15(14)13-19(18)23-2/h4-13H,3H2,1-2H3,(H,21,22)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a>1.16E+5n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2Q23XQJ
More data for this
Ligand-Target Pair
Aryl hydrocarbon receptor


(Homo sapiens (Human))
BDBM75513
PNG
(3-methoxy-N-(4-methylphenyl)-2-naphthalenecarboxam...)
Show SMILES COc1cc2ccccc2cc1C(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C19H17NO2/c1-13-7-9-16(10-8-13)20-19(21)17-11-14-5-3-4-6-15(14)12-18(17)22-2/h3-12H,1-2H3,(H,20,21)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 394n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2K93612
More data for this
Ligand-Target Pair
Aryl hydrocarbon receptor


(Homo sapiens (Human))
BDBM75523
PNG
(3-Methoxy-naphthalene-2-carboxylic acid (4-ethoxy-...)
Show SMILES CCOc1ccc(NC(=O)c2cc3ccccc3cc2OC)cc1
Show InChI InChI=1S/C20H19NO3/c1-3-24-17-10-8-16(9-11-17)21-20(22)18-12-14-6-4-5-7-15(14)13-19(18)23-2/h4-13H,3H2,1-2H3,(H,21,22)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 2.17E+3n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2K93612
More data for this
Ligand-Target Pair
Caspase-3


(Homo sapiens (Human))
BDBM76665
PNG
(MLS001212007 | N-(4-methoxyphenyl)-2-naphthaleneca...)
Show SMILES COc1ccc(NC(=O)c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C18H15NO2/c1-21-17-10-8-16(9-11-17)19-18(20)15-7-6-13-4-2-3-5-14(13)12-15/h2-12H,1H3,(H,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 5.56E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2RJ4GZT
More data for this
Ligand-Target Pair
SUMO/sentrin specific peptidase family member 8


(Homo sapiens (Human))
BDBM76665
PNG
(MLS001212007 | N-(4-methoxyphenyl)-2-naphthaleneca...)
Show SMILES COc1ccc(NC(=O)c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C18H15NO2/c1-21-17-10-8-16(9-11-17)19-18(20)15-7-6-13-4-2-3-5-14(13)12-15/h2-12H,1H3,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a>1.00E+5n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2MS3R7H
More data for this
Ligand-Target Pair
SUMO-1-specific protease


(Homo sapiens (Human))
BDBM76665
PNG
(MLS001212007 | N-(4-methoxyphenyl)-2-naphthaleneca...)
Show SMILES COc1ccc(NC(=O)c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C18H15NO2/c1-21-17-10-8-16(9-11-17)19-18(20)15-7-6-13-4-2-3-5-14(13)12-15/h2-12H,1H3,(H,19,20)
KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a>1.00E+5n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q27H1H10
More data for this
Ligand-Target Pair
probable DNA dC->dU-editing enzyme APOBEC-3A


(Homo sapiens (Human))
BDBM80521
PNG
(3-Hydroxy-2-naphtho-p-phenetidide | 3-hydroxy-N-p-...)
Show SMILES CCOc1ccc(NC(=O)c2cc3ccccc3cc2O)cc1
Show InChI InChI=1S/C19H17NO3/c1-2-23-16-9-7-15(8-10-16)20-19(22)17-11-13-5-3-4-6-14(13)12-18(17)21/h3-12,21H,2H2,1H3,(H,20,22)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 1.29E+4n/an/an/an/an/a25



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q24F1P6P
More data for this
Ligand-Target Pair
DNA dC->dU-editing enzyme APOBEC-3G


(Homo sapiens (Human))
BDBM80521
PNG
(3-Hydroxy-2-naphtho-p-phenetidide | 3-hydroxy-N-p-...)
Show SMILES CCOc1ccc(NC(=O)c2cc3ccccc3cc2O)cc1
Show InChI InChI=1S/C19H17NO3/c1-2-23-16-9-7-15(8-10-16)20-19(22)17-11-13-5-3-4-6-14(13)12-18(17)21/h3-12,21H,2H2,1H3,(H,20,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 4.75E+4n/an/an/an/an/a25



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2862DX0
More data for this
Ligand-Target Pair
SKiNhead family member (skn-1)


(Caenorhabditis elegans)
BDBM46010
PNG
(2-methoxy-N-(2-naphthalenyl)benzamide | 2-methoxy-...)
Show SMILES COc1ccccc1C(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C18H15NO2/c1-21-17-9-5-4-8-16(17)18(20)19-15-11-10-13-6-2-3-7-14(13)12-15/h2-12H,1H3,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 8.02E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2DV1HH8
More data for this
Ligand-Target Pair
tumor necrosis factor receptor superfamily member 10B isoform 1 precursor [Homo sapiens]


(Homo sapiens (Human))
BDBM95946
PNG
(2-hydroxy-N-(2-naphthalenyl)benzamide | 2-hydroxy-...)
Show SMILES Oc1ccccc1C(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C17H13NO2/c19-16-8-4-3-7-15(16)17(20)18-14-10-9-12-5-1-2-6-13(12)11-14/h1-11,19H,(H,18,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 8.90E+3n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2013)


BindingDB Entry DOI: 10.7270/Q2P55M4P
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))
BDBM95946
PNG
(2-hydroxy-N-(2-naphthalenyl)benzamide | 2-hydroxy-...)
Show SMILES Oc1ccccc1C(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C17H13NO2/c19-16-8-4-3-7-15(16)17(20)18-14-10-9-12-5-1-2-6-13(12)11-14/h1-11,19H,(H,18,20)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 6.76E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...


PubChem Bioassay (2013)


BindingDB Entry DOI: 10.7270/Q23F4N80
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))
BDBM114920
PNG
(3-methoxy-N-(4-methoxyphenyl)-2-naphthalenecarboxa...)
Show SMILES COc1ccc(NC(=O)c2cc3ccccc3cc2OC)cc1
Show InChI InChI=1S/C19H17NO3/c1-22-16-9-7-15(8-10-16)20-19(21)17-11-13-5-3-4-6-14(13)12-18(17)23-2/h3-12H,1-2H3,(H,20,21)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 6.75E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...


PubChem Bioassay (2013)


BindingDB Entry DOI: 10.7270/Q2TX3D2C
More data for this
Ligand-Target Pair
Protein DAF-12, isoform a


(Caenorhabditis elegans)
BDBM95946
PNG
(2-hydroxy-N-(2-naphthalenyl)benzamide | 2-hydroxy-...)
Show SMILES Oc1ccccc1C(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C17H13NO2/c19-16-8-4-3-7-15(16)17(20)18-14-10-9-12-5-1-2-6-13(12)11-14/h1-11,19H,(H,18,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 6.76E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2013)


BindingDB Entry DOI: 10.7270/Q2BV7F8Z
More data for this
Ligand-Target Pair
Protein DAF-12, isoform a


(Caenorhabditis elegans)
BDBM114920
PNG
(3-methoxy-N-(4-methoxyphenyl)-2-naphthalenecarboxa...)
Show SMILES COc1ccc(NC(=O)c2cc3ccccc3cc2OC)cc1
Show InChI InChI=1S/C19H17NO3/c1-22-16-9-7-15(8-10-16)20-19(21)17-11-13-5-3-4-6-14(13)12-18(17)23-2/h3-12H,1-2H3,(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 6.75E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...


PubChem Bioassay (2013)


BindingDB Entry DOI: 10.7270/Q2736PK0
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50086683
PNG
(3,5-Dihydroxy-naphthalene-2-carboxylic acid (3-hyd...)
Show SMILES Oc1cccc(NC(=O)c2cc3cccc(O)c3cc2O)c1
Show InChI InChI=1S/C17H13NO4/c19-12-5-2-4-11(8-12)18-17(22)14-7-10-3-1-6-15(20)13(10)9-16(14)21/h1-9,19-21H,(H,18,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.50E+5n/an/an/an/an/an/a



State University of New York

Curated by ChEMBL


Assay Description
Inhibition of human purified recombinant pp60c-src tyrosine kinase


Bioorg Med Chem Lett 10: 477-81 (2000)


Article DOI: 10.1016/s0960-894x(00)00039-1
BindingDB Entry DOI: 10.7270/Q2NS0T45
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50086684
PNG
(3,6-Dihydroxy-naphthalene-2-carboxylic acid (3-hyd...)
Show SMILES Oc1cccc(NC(=O)c2cc3ccc(O)cc3cc2O)c1
Show InChI InChI=1S/C17H13NO4/c19-13-3-1-2-12(9-13)18-17(22)15-7-10-4-5-14(20)6-11(10)8-16(15)21/h1-9,19-21H,(H,18,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



State University of New York

Curated by ChEMBL


Assay Description
Inhibition of human purified recombinant pp60c-src tyrosine kinase


Bioorg Med Chem Lett 10: 477-81 (2000)


Article DOI: 10.1016/s0960-894x(00)00039-1
BindingDB Entry DOI: 10.7270/Q2NS0T45
More data for this
Ligand-Target Pair
Human herpesvirus 6 DNA polymerase


(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
BDBM50091975
PNG
(3-Hydroxy-naphthalene-2-carboxylic acid (4-cyano-p...)
Show SMILES Oc1cc2ccccc2cc1C(=O)Nc1ccc(cc1)C#N
Show InChI InChI=1S/C18H12N2O2/c19-11-12-5-7-15(8-6-12)20-18(22)16-9-13-3-1-2-4-14(13)10-17(16)21/h1-10,21H,(H,20,22)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Pharmacia

Curated by ChEMBL


Assay Description
Inhibitory activity against Human Cytomegalovirus (HCMV) polymerase


Bioorg Med Chem Lett 10: 2079-81 (2000)


Article DOI: 10.1016/s0960-894x(00)00402-9
BindingDB Entry DOI: 10.7270/Q2222T0M
More data for this
Ligand-Target Pair
Human herpesvirus 6 DNA polymerase


(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
BDBM50091993
PNG
(3-Hydroxy-naphthalene-2-carboxylic acid phenylamid...)
Show SMILES Oc1cc2ccccc2cc1C(=O)Nc1ccccc1
Show InChI InChI=1S/C17H13NO2/c19-16-11-13-7-5-4-6-12(13)10-15(16)17(20)18-14-8-2-1-3-9-14/h1-11,19H,(H,18,20)
UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Pharmacia

Curated by ChEMBL


Assay Description
Inhibitory activity against Human Cytomegalovirus (HCMV) polymerase


Bioorg Med Chem Lett 10: 2079-81 (2000)


Article DOI: 10.1016/s0960-894x(00)00402-9
BindingDB Entry DOI: 10.7270/Q2222T0M
More data for this
Ligand-Target Pair
Human herpesvirus 6 DNA polymerase


(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
BDBM50091999
PNG
(3-Hydroxy-naphthalene-2-carboxylic acid (4-chloro-...)
Show SMILES Oc1cc2ccccc2cc1C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C17H12ClNO2/c18-13-5-7-14(8-6-13)19-17(21)15-9-11-3-1-2-4-12(11)10-16(15)20/h1-10,20H,(H,19,21)
UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 6.90E+4n/an/an/an/an/an/a



Pharmacia

Curated by ChEMBL


Assay Description
Inhibitory activity against Human Cytomegalovirus (HCMV) polymerase


Bioorg Med Chem Lett 10: 2079-81 (2000)


Article DOI: 10.1016/s0960-894x(00)00402-9
BindingDB Entry DOI: 10.7270/Q2222T0M
More data for this
Ligand-Target Pair
Human herpesvirus 6 DNA polymerase


(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
BDBM50092002
PNG
(1-Hydroxy-naphthalene-2-carboxylic acid (4-chloro-...)
Show SMILES Oc1c(ccc2ccccc12)C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C17H12ClNO2/c18-12-6-8-13(9-7-12)19-17(21)15-10-5-11-3-1-2-4-14(11)16(15)20/h1-10,20H,(H,19,21)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.70E+4n/an/an/an/an/an/a



Pharmacia

Curated by ChEMBL


Assay Description
Inhibitory activity against Human Cytomegalovirus (HCMV) polymerase


Bioorg Med Chem Lett 10: 2079-81 (2000)


Article DOI: 10.1016/s0960-894x(00)00402-9
BindingDB Entry DOI: 10.7270/Q2222T0M
More data for this
Ligand-Target Pair
Major prion protein


(Ovis aries)
BDBM80521
PNG
(3-Hydroxy-2-naphtho-p-phenetidide | 3-hydroxy-N-p-...)
Show SMILES CCOc1ccc(NC(=O)c2cc3ccccc3cc2O)cc1
Show InChI InChI=1S/C19H17NO3/c1-2-23-16-9-7-15(8-10-16)20-19(22)17-11-13-5-3-4-6-14(13)12-18(17)21/h3-12,21H,2H2,1H3,(H,20,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 212n/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISA


ACS Med Chem Lett 4: 647-650 (2013)


Article DOI: 10.1021/ml300454k
BindingDB Entry DOI: 10.7270/Q26D5VCS
More data for this
Ligand-Target Pair