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4 similar compounds to monomer 48098

Compile data set for download or QSAR
Wt: 263.2
BDBM48083
Wt: 279.2
BDBM54465
Wt: 263.2
BDBM66053
Wt: 279.2
BDBM64125

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 48083,54465,66053,64125   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-galactosidase


(Escherichia coli)
BDBM48083
PNG
((5E)-5-(o-tolylhydrazono)quinolin-8-one | (5E)-5-[...)
Show SMILES Cc1ccccc1N=Nc1ccc(O)c2ncccc12
Show InChI InChI=1S/C16H13N3O/c1-11-5-2-3-7-13(11)18-19-14-8-9-15(20)16-12(14)6-4-10-17-16/h2-10,20H,1H3
PDB
MMDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

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PCBioAssay
n/an/an/an/a 3.01E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q24X5667
More data for this
Ligand-Target Pair
nucleotide-binding oligomerization domain containing 2


(Homo sapiens (Human))
BDBM54465
PNG
((5E)-5-[(3-methoxyphenyl)hydrazinylidene]-8-quinol...)
Show SMILES COc1cccc(c1)N=Nc1ccc(O)c2ncccc12
Show InChI InChI=1S/C16H13N3O2/c1-21-12-5-2-4-11(10-12)18-19-14-7-8-15(20)16-13(14)6-3-9-17-16/h2-10,20H,1H3
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n/an/a 3.40E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q23R0R8T
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM48083
PNG
((5E)-5-(o-tolylhydrazono)quinolin-8-one | (5E)-5-[...)
Show SMILES Cc1ccccc1N=Nc1ccc(O)c2ncccc12
Show InChI InChI=1S/C16H13N3O/c1-11-5-2-3-7-13(11)18-19-14-8-9-15(20)16-12(14)6-4-10-17-16/h2-10,20H,1H3
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n/an/a 4.11E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q20C4T6J
More data for this
Ligand-Target Pair
nucleotide-binding oligomerization domain containing 1


(Homo sapiens (Human))
BDBM54465
PNG
((5E)-5-[(3-methoxyphenyl)hydrazinylidene]-8-quinol...)
Show SMILES COc1cccc(c1)N=Nc1ccc(O)c2ncccc12
Show InChI InChI=1S/C16H13N3O2/c1-21-12-5-2-4-11(10-12)18-19-14-7-8-15(20)16-13(14)6-3-9-17-16/h2-10,20H,1H3
PDB
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n/an/an/an/a 3.74E+3n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2CN72C0
More data for this
Ligand-Target Pair
Tumor necrosis factor


(Homo sapiens (Human))
BDBM54465
PNG
((5E)-5-[(3-methoxyphenyl)hydrazinylidene]-8-quinol...)
Show SMILES COc1cccc(c1)N=Nc1ccc(O)c2ncccc12
Show InChI InChI=1S/C16H13N3O2/c1-21-12-5-2-4-11(10-12)18-19-14-7-8-15(20)16-13(14)6-3-9-17-16/h2-10,20H,1H3
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n/an/a 3.04E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q25M6443
More data for this
Ligand-Target Pair
Hsf1 protein


(Mus musculus)
BDBM66053
PNG
((5E)-5-(m-tolylhydrazono)quinolin-8-one | (5E)-5-[...)
Show SMILES Cc1cccc(c1)N=Nc1ccc(O)c2ncccc12
Show InChI InChI=1S/C16H13N3O/c1-11-4-2-5-12(10-11)18-19-14-7-8-15(20)16-13(14)6-3-9-17-16/h2-10,20H,1H3
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n/an/an/an/a 4.58E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2P55KXK
More data for this
Ligand-Target Pair
LAP4


(Saccharomyces cerevisiae)
BDBM48083
PNG
((5E)-5-(o-tolylhydrazono)quinolin-8-one | (5E)-5-[...)
Show SMILES Cc1ccccc1N=Nc1ccc(O)c2ncccc12
Show InChI InChI=1S/C16H13N3O/c1-11-5-2-3-7-13(11)18-19-14-8-9-15(20)16-12(14)6-4-10-17-16/h2-10,20H,1H3
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n/an/an/an/a 7.96E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q21R6P02
More data for this
Ligand-Target Pair
LAP4


(Saccharomyces cerevisiae)
BDBM66053
PNG
((5E)-5-(m-tolylhydrazono)quinolin-8-one | (5E)-5-[...)
Show SMILES Cc1cccc(c1)N=Nc1ccc(O)c2ncccc12
Show InChI InChI=1S/C16H13N3O/c1-11-4-2-5-12(10-11)18-19-14-7-8-15(20)16-13(14)6-3-9-17-16/h2-10,20H,1H3
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n/an/an/an/a 1.40E+4n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q21R6P02
More data for this
Ligand-Target Pair
LAP4


(Saccharomyces cerevisiae)
BDBM64125
PNG
((5E)-5-[(2-methoxyphenyl)hydrazinylidene]-8-quinol...)
Show SMILES COc1ccccc1N=Nc1ccc(O)c2ncccc12
Show InChI InChI=1S/C16H13N3O2/c1-21-15-7-3-2-6-13(15)19-18-12-8-9-14(20)16-11(12)5-4-10-17-16/h2-10,20H,1H3
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n/an/an/an/a 4.25E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q21R6P02
More data for this
Ligand-Target Pair
LAP4


(Saccharomyces cerevisiae)
BDBM54465
PNG
((5E)-5-[(3-methoxyphenyl)hydrazinylidene]-8-quinol...)
Show SMILES COc1cccc(c1)N=Nc1ccc(O)c2ncccc12
Show InChI InChI=1S/C16H13N3O2/c1-21-12-5-2-4-11(10-12)18-19-14-7-8-15(20)16-13(14)6-3-9-17-16/h2-10,20H,1H3
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n/an/an/an/a 3.36E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q21R6P02
More data for this
Ligand-Target Pair
Hsf1 protein


(Mus musculus)
BDBM64125
PNG
((5E)-5-[(2-methoxyphenyl)hydrazinylidene]-8-quinol...)
Show SMILES COc1ccccc1N=Nc1ccc(O)c2ncccc12
Show InChI InChI=1S/C16H13N3O2/c1-21-15-7-3-2-6-13(15)19-18-12-8-9-14(20)16-11(12)5-4-10-17-16/h2-10,20H,1H3
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n/an/an/an/a 2.29E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2MW2FKX
More data for this
Ligand-Target Pair