BindingDB logo
myBDB logout

17 similar compounds to monomer 50007881

Compile data set for download or QSAR
Wt: 301.3
BDBM50007883
Wt: 319.3
BDBM50007885
Wt: 315.3
BDBM50007889
Wt: 343.3
BDBM50007890
Wt: 316.3
BDBM50007893
Wt: 329.3
BDBM50007894
Wt: 301.3
BDBM50007896
Wt: 315.3
BDBM50007858
Wt: 377.4
BDBM50007859
Wt: 315.3
BDBM50007860
Wt: 303.3
BDBM50007864
Wt: 315.3
BDBM50007867
Wt: 319.3
BDBM50007869
Wt: 315.3
BDBM50007870
Wt: 301.3
BDBM50007874
Displayed 1 to 15 (of 17 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50007883,50007885,50007889,50007890,50007893,50007894,50007896,50007858,50007859,50007860,50007864,50007867,50007869,50007870,50007874   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007870
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES CN1C2CCCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C17H21N3O3/c1-19-11-5-4-6-12(19)10-13(9-11)23-17(22)20-15-8-3-2-7-14(15)18-16(20)21/h2-3,7-8,11-13H,4-6,9-10H2,1H3,(H,18,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.20n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007858
PNG
(3-Methyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccccc2n(C)c1=O
Show InChI InChI=1S/C17H21N3O3/c1-18-11-7-8-12(18)10-13(9-11)23-17(22)20-15-6-4-3-5-14(15)19(2)16(20)21/h3-6,11-13H,7-10H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
12n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007874
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C16H19N3O3/c1-18-10-6-7-11(18)9-12(8-10)22-16(21)19-14-5-3-2-4-13(14)17-15(19)20/h2-5,10-12H,6-9H2,1H3,(H,17,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
21n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007869
PNG
(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccc(F)cc2[nH]c1=O
Show InChI InChI=1S/C16H18FN3O3/c1-19-10-3-4-11(19)8-12(7-10)23-16(22)20-14-5-2-9(17)6-13(14)18-15(20)21/h2,5-6,10-12H,3-4,7-8H2,1H3,(H,18,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
26n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007893
PNG
(8,8-Dimethyl-3-(2-oxo-2,3-dihydro-benzoimidazole-1...)
Show SMILES C[N+]1(C)C2CCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C17H21N3O3/c1-20(2)11-7-8-12(20)10-13(9-11)23-17(22)19-15-6-4-3-5-14(15)18-16(19)21/h3-6,11-13H,7-10H2,1-2H3/p+1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
34n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007885
PNG
(6-Fluoro-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2cc(F)ccc2[nH]c1=O
Show InChI InChI=1S/C16H18FN3O3/c1-19-10-3-4-11(19)8-12(7-10)23-16(22)20-14-6-9(17)2-5-13(14)18-15(20)21/h2,5-6,10-12H,3-4,7-8H2,1H3,(H,18,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
34n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007860
PNG
(7-Methyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2c(C)cccc2[nH]c1=O
Show InChI InChI=1S/C17H21N3O3/c1-10-4-3-5-14-15(10)20(16(21)18-14)17(22)23-13-8-11-6-7-12(9-13)19(11)2/h3-5,11-13H,6-9H2,1-2H3,(H,18,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
306n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007889
PNG
(5-Methyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccc(C)cc2[nH]c1=O
Show InChI InChI=1S/C17H21N3O3/c1-10-3-6-15-14(7-10)18-16(21)20(15)17(22)23-13-8-11-4-5-12(9-13)19(11)2/h3,6-7,11-13H,4-5,8-9H2,1-2H3,(H,18,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007859
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES O=C(OC1CC2CCC(C1)N2Cc1ccccc1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C22H23N3O3/c26-21-23-19-8-4-5-9-20(19)25(21)22(27)28-18-12-16-10-11-17(13-18)24(16)14-15-6-2-1-3-7-15/h1-9,16-18H,10-14H2,(H,23,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007894
PNG
(5,6-Dimethyl-2-oxo-2,3-dihydro-benzoimidazole-1-ca...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2cc(C)c(C)cc2[nH]c1=O
Show InChI InChI=1S/C18H23N3O3/c1-10-6-15-16(7-11(10)2)21(17(22)19-15)18(23)24-14-8-12-4-5-13(9-14)20(12)3/h6-7,12-14H,4-5,8-9H2,1-3H3,(H,19,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007867
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES CCN1C2CCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C17H21N3O3/c1-2-19-11-7-8-12(19)10-13(9-11)23-17(22)20-15-6-4-3-5-14(15)18-16(20)21/h3-6,11-13H,2,7-10H2,1H3,(H,18,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007890
PNG
(6-Acetyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2cc(ccc2[nH]c1=O)C(C)=O
Show InChI InChI=1S/C18H21N3O4/c1-10(22)11-3-6-15-16(7-11)21(17(23)19-15)18(24)25-14-8-12-4-5-13(9-14)20(12)2/h3,6-7,12-14H,4-5,8-9H2,1-2H3,(H,19,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007883
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES CN1CC2CCC1CC2OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C16H19N3O3/c1-18-9-10-6-7-11(18)8-14(10)22-16(21)19-13-5-3-2-4-12(13)17-15(19)20/h2-5,10-11,14H,6-9H2,1H3,(H,17,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007896
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C16H19N3O3/c1-18-10-6-7-11(18)9-12(8-10)22-16(21)19-14-5-3-2-4-13(14)17-15(19)20/h2-5,10-12H,6-9H2,1H3,(H,17,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007864
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES CC1CC(CC(C)N1C)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C16H21N3O3/c1-10-8-12(9-11(2)18(10)3)22-16(21)19-14-7-5-4-6-13(14)17-15(19)20/h4-7,10-12H,8-9H2,1-3H3,(H,17,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair