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12 similar compounds to monomer 50007885

Compile data set for download or QSAR
Wt: 315.3
BDBM50007889
Wt: 316.3
BDBM50007893
Wt: 301.3
BDBM50007896
Wt: 315.3
BDBM50007858
Wt: 303.3
BDBM50007864
Wt: 315.3
BDBM50007867
Wt: 319.3
BDBM50007869
Wt: 315.3
BDBM50007870
Wt: 301.3
BDBM50007874
Wt: 331.3
BDBM50007876
Wt: 315.3
BDBM50007880
Wt: 315.3
BDBM50007881

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50007889,50007893,50007896,50007858,50007864,50007867,50007869,50007870,50007874,50007876,50007880,50007881   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007870
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES CN1C2CCCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C17H21N3O3/c1-19-11-5-4-6-12(19)10-13(9-11)23-17(22)20-15-8-3-2-7-14(15)18-16(20)21/h2-3,7-8,11-13H,4-6,9-10H2,1H3,(H,18,21)
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2.20n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007881
PNG
(4-Methyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2cccc(C)c2[nH]c1=O
Show InChI InChI=1S/C17H21N3O3/c1-10-4-3-5-14-15(10)18-16(21)20(14)17(22)23-13-8-11-6-7-12(9-13)19(11)2/h3-5,11-13H,6-9H2,1-2H3,(H,18,21)
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7.90n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007858
PNG
(3-Methyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccccc2n(C)c1=O
Show InChI InChI=1S/C17H21N3O3/c1-18-11-7-8-12(18)10-13(9-11)23-17(22)20-15-6-4-3-5-14(15)19(2)16(20)21/h3-6,11-13H,7-10H2,1-2H3
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12n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007874
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C16H19N3O3/c1-18-10-6-7-11(18)9-12(8-10)22-16(21)19-14-5-3-2-4-13(14)17-15(19)20/h2-5,10-12H,6-9H2,1H3,(H,17,20)
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21n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007869
PNG
(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccc(F)cc2[nH]c1=O
Show InChI InChI=1S/C16H18FN3O3/c1-19-10-3-4-11(19)8-12(7-10)23-16(22)20-14-5-2-9(17)6-13(14)18-15(20)21/h2,5-6,10-12H,3-4,7-8H2,1H3,(H,18,21)
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26n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007893
PNG
(8,8-Dimethyl-3-(2-oxo-2,3-dihydro-benzoimidazole-1...)
Show SMILES C[N+]1(C)C2CCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C17H21N3O3/c1-20(2)11-7-8-12(20)10-13(9-11)23-17(22)19-15-6-4-3-5-14(15)18-16(19)21/h3-6,11-13H,7-10H2,1-2H3/p+1
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34n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007880
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES CN1C2CCCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C17H21N3O3/c1-19-11-5-4-6-12(19)10-13(9-11)23-17(22)20-15-8-3-2-7-14(15)18-16(20)21/h2-3,7-8,11-13H,4-6,9-10H2,1H3,(H,18,21)
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>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007889
PNG
(5-Methyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccc(C)cc2[nH]c1=O
Show InChI InChI=1S/C17H21N3O3/c1-10-3-6-15-14(7-10)18-16(21)20(15)17(22)23-13-8-11-4-5-12(9-13)19(11)2/h3,6-7,11-13H,4-5,8-9H2,1-2H3,(H,18,21)
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>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007876
PNG
(5-Methoxy-2-oxo-2,3-dihydro-benzoimidazole-1-carbo...)
Show SMILES COc1ccc2n(C(=O)OC3CC4CCC(C3)N4C)c(=O)[nH]c2c1
Show InChI InChI=1S/C17H21N3O4/c1-19-10-3-4-11(19)8-13(7-10)24-17(22)20-15-6-5-12(23-2)9-14(15)18-16(20)21/h5-6,9-11,13H,3-4,7-8H2,1-2H3,(H,18,21)
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>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007896
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C16H19N3O3/c1-18-10-6-7-11(18)9-12(8-10)22-16(21)19-14-5-3-2-4-13(14)17-15(19)20/h2-5,10-12H,6-9H2,1H3,(H,17,20)
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>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007864
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES CC1CC(CC(C)N1C)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C16H21N3O3/c1-10-8-12(9-11(2)18(10)3)22-16(21)19-14-7-5-4-6-13(14)17-15(19)20/h4-7,10-12H,8-9H2,1-3H3,(H,17,20)
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>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50007867
PNG
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)
Show SMILES CCN1C2CCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C17H21N3O3/c1-2-19-11-7-8-12(19)10-13(9-11)23-17(22)20-15-6-4-3-5-14(15)18-16(20)21/h3-6,11-13H,2,7-10H2,1H3,(H,18,21)
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>1.00E+3n/an/an/an/an/an/an/an/a



Istituto De Angeli

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex


J Med Chem 33: 2101-8 (1990)


Article DOI: 10.1021/jm00170a009
BindingDB Entry DOI: 10.7270/Q22Z164J
More data for this
Ligand-Target Pair