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2 similar compounds to monomer 50083953

Compile data set for download or QSAR
Wt: 285.0
BDBM50083951
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Wt: 347.1
BDBM50405004

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083951,50405004   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hydroxyacid oxidase 1


(Homo sapiens (Human))
BDBM50405004
PNG
(CHEMBL282504)
Show SMILES OC(=O)C(=O)CC(=O)c1ccc(cc1)-c1ccc(Br)cc1
Show InChI InChI=1S/C16H11BrO4/c17-13-7-5-11(6-8-13)10-1-3-12(4-2-10)14(18)9-15(19)16(20)21/h1-8H,9H2,(H,20,21)
PDB
MMDB

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KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 63n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine Glycolate oxidase


J Med Chem 26: 1196-200 (1983)


Article DOI: 10.1021/jm00362a020
BindingDB Entry DOI: 10.7270/Q27082K8
More data for this
Ligand-Target Pair
Kynurenine 3-monooxygenase


(Rattus norvegicus)
BDBM50083951
PNG
(4-(3-Bromo-phenyl)-2-hydroxy-4-oxo-but-2-enoic aci...)
Show SMILES COC(=O)C(=O)CC(=O)c1cccc(Br)c1
Show InChI InChI=1S/C11H9BrO4/c1-16-11(15)10(14)6-9(13)7-3-2-4-8(12)5-7/h2-5H,6H2,1H3
PDB

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UniProtKB/SwissProt

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Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Glaxo Wellcome Research and Development

Curated by ChEMBL


Assay Description
Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liver


J Med Chem 43: 123-7 (2000)


Article DOI: 10.1021/jm990396t
BindingDB Entry DOI: 10.7270/Q2RX9B9B
More data for this
Ligand-Target Pair