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1 similar compounds to monomer 382

Compile data set for download or QSAR
Wt: 205.1
BDBM50113313
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113313   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vesicular glutamate transporter 3


(Rattus norvegicus)
BDBM50113313
PNG
(4,8-Dihydroxy-quinoline-2-carboxylic acid anion | ...)
Show SMILES OC(=O)c1cc(O)c2cccc(O)c2n1
Show InChI InChI=1S/C10H7NO4/c12-7-3-1-2-5-8(13)4-6(10(14)15)11-9(5)7/h1-4,12H,(H,11,13)(H,14,15)
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Article
PubMed
1.90E+5n/an/an/an/an/an/an/an/a



The University of Montana

Curated by ChEMBL


Assay Description
Evaluated for competitive inhibition against Vesicular glutamate transporter (VGLUT), and Ki value was reported.


J Med Chem 45: 2260-76 (2002)


Article DOI: 10.1021/jm010261z
BindingDB Entry DOI: 10.7270/Q2NK3FRR
More data for this
Ligand-Target Pair
LDL-associated phospholipase A2


(Homo sapiens (Human))
BDBM50113313
PNG
(4,8-Dihydroxy-quinoline-2-carboxylic acid anion | ...)
Show SMILES OC(=O)c1cc(O)c2cccc(O)c2n1
Show InChI InChI=1S/C10H7NO4/c12-7-3-1-2-5-8(13)4-6(10(14)15)11-9(5)7/h1-4,12H,(H,11,13)(H,14,15)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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antibodypedia
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CHEBI
CHEMBL
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



ActivX Biosciences Inc

Curated by ChEMBL


Assay Description
Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...


Bioorg Med Chem Lett 22: 868-71 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.045
BindingDB Entry DOI: 10.7270/Q2XG9RMD
More data for this
Ligand-Target Pair
LDL-associated phospholipase A2


(Homo sapiens (Human))
BDBM50113313
PNG
(4,8-Dihydroxy-quinoline-2-carboxylic acid anion | ...)
Show SMILES OC(=O)c1cc(O)c2cccc(O)c2n1
Show InChI InChI=1S/C10H7NO4/c12-7-3-1-2-5-8(13)4-6(10(14)15)11-9(5)7/h1-4,12H,(H,11,13)(H,14,15)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
Purchase

CHEBI
CHEMBL
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



ActivX Biosciences Inc

Curated by ChEMBL


Assay Description
Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...


Bioorg Med Chem Lett 22: 868-71 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.045
BindingDB Entry DOI: 10.7270/Q2XG9RMD
More data for this
Ligand-Target Pair