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1 similar compounds to monomer 50240386

Compile data set for download or QSAR
Wt: 280.4
BDBM50137023

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50137023   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GABA transporter


(Mus musculus)
BDBM50137023
PNG
(CHEMBL3753364)
Show SMILES CCN(CC)CCC(=O)N1C(=O)CCC11CCCCC1
Show InChI InChI=1S/C16H28N2O2/c1-3-17(4-2)13-9-15(20)18-14(19)8-12-16(18)10-6-5-7-11-16/h3-13H2,1-2H3
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEBI
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT2 mediated [3]GABA uptake expressed in HEK293 cells after 3 mins by scintillation counting


Bioorg Med Chem Lett 26: 417-23 (2016)


Article DOI: 10.1016/j.bmcl.2015.11.100
BindingDB Entry DOI: 10.7270/Q2V69MF4
More data for this
Ligand-Target Pair
GABA transporter


(Mus musculus)
BDBM50137023
PNG
(CHEMBL3753364)
Show SMILES CCN(CC)CCC(=O)N1C(=O)CCC11CCCCC1
Show InChI InChI=1S/C16H28N2O2/c1-3-17(4-2)13-9-15(20)18-14(19)8-12-16(18)10-6-5-7-11-16/h3-13H2,1-2H3
Reactome pathway

UniProtKB/SwissProt

GoogleScholar
CHEBI
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
Inhibition of mouse BGT1 mediated [3]GABA uptake expressed in HEK293 cells after 3 mins by scintillation counting


Bioorg Med Chem Lett 26: 417-23 (2016)


Article DOI: 10.1016/j.bmcl.2015.11.100
BindingDB Entry DOI: 10.7270/Q2V69MF4
More data for this
Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1


(Rattus norvegicus)
BDBM50137023
PNG
(CHEMBL3753364)
Show SMILES CCN(CC)CCC(=O)N1C(=O)CCC11CCCCC1
Show InChI InChI=1S/C16H28N2O2/c1-3-17(4-2)13-9-15(20)18-14(19)8-12-16(18)10-6-5-7-11-16/h3-13H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEBI
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT1 mediated [3]GABA uptake expressed in HEK293 cells after 3 mins by scintillation counting


Bioorg Med Chem Lett 26: 417-23 (2016)


Article DOI: 10.1016/j.bmcl.2015.11.100
BindingDB Entry DOI: 10.7270/Q2V69MF4
More data for this
Ligand-Target Pair
GABA transporter


(Mus musculus)
BDBM50137023
PNG
(CHEMBL3753364)
Show SMILES CCN(CC)CCC(=O)N1C(=O)CCC11CCCCC1
Show InChI InChI=1S/C16H28N2O2/c1-3-17(4-2)13-9-15(20)18-14(19)8-12-16(18)10-6-5-7-11-16/h3-13H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEBI
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT3 mediated [3]GABA uptake expressed in HEK293 cells after 3 mins by scintillation counting


Bioorg Med Chem Lett 26: 417-23 (2016)


Article DOI: 10.1016/j.bmcl.2015.11.100
BindingDB Entry DOI: 10.7270/Q2V69MF4
More data for this
Ligand-Target Pair