Compounds in cluster

1 similar compounds to monomer 50184635

Wt: 210.1
BDBM50152579

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50152579
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
GlcB (Homo sapiens (Human))	BDBM50152579 (4-(2-Fluoro-phenyl)-2,4-dioxo-butyric acid \| CHEMB...) Show SMILES OC(=O)C(=O)CC(=O)c1ccccc1F Show InChI	PDB GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	D3R	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description DNTB-Coupled_Enzyme_Assay				D3R 223: (2015) BindingDB Entry DOI: 10.7270/Q2NC602G
D3R					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50152579 (4-(2-Fluoro-phenyl)-2,4-dioxo-butyric acid \| CHEMB...) Show SMILES OC(=O)C(=O)CC(=O)c1ccccc1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Inhibition of PTP1B				Bioorg Med Chem 19: 2145-55 (2011) Article DOI: 10.1016/j.bmc.2011.02.047 BindingDB Entry DOI: 10.7270/Q2BR8SHK
					More data for this Ligand-Target Pair
DNA excision repair protein ERCC-5 (Homo sapiens (Human))	BDBM50152579 (4-(2-Fluoro-phenyl)-2,4-dioxo-butyric acid \| CHEMB...) Show SMILES OC(=O)C(=O)CC(=O)c1ccccc1F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Athersys Inc Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G				Bioorg Med Chem Lett 14: 4915-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF
Athersys Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Flap endonuclease 1 (Homo sapiens (Human))	BDBM50152579 (4-(2-Fluoro-phenyl)-2,4-dioxo-butyric acid \| CHEMB...) Show SMILES OC(=O)C(=O)CC(=O)c1ccccc1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Athersys Inc Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Flap endonuclease-1				Bioorg Med Chem Lett 14: 4915-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF
Athersys Inc Curated by ChEMBL					More data for this Ligand-Target Pair