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1 similar compounds to monomer 50370586

Compile data set for download or QSAR
Wt: 560.3
BDBM50169133

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169133   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))
BDBM50169133
PNG
(CHEMBL3805506)
Show SMILES O[C@H](CN1CC(Cc2cccc(Br)c2)(c2ccccc12)c1cccc(OC(F)(F)F)c1)C(F)(F)F
Show InChI InChI=1S/C25H20BrF6NO2/c26-18-7-3-5-16(11-18)13-23(17-6-4-8-19(12-17)35-25(30,31)32)15-33(14-22(34)24(27,28)29)21-10-2-1-9-20(21)23/h1-12,22,34H,13-15H2/t22-,23?/m1/s1
PDB
MMDB

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Similars

Article
PubMed
n/an/a 308n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of CETP in 95% human serum assessed as suppression of transfer of [3H]-cholesterol oleate/[3H]-triolein from LDL to HDL after 1 hr by liqu...


ACS Med Chem Lett 7: 261-5 (2016)


Article DOI: 10.1021/acsmedchemlett.5b00404
BindingDB Entry DOI: 10.7270/Q2X92D7Z
More data for this
Ligand-Target Pair