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1 similar compounds to monomer 50293721

Compile data set for download or QSAR
Wt: 258.2
BDBM50293717
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293717   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50293717
PNG
(CHEMBL572346 | N-(3,4-dimethoxyphenyl)picolinamide...)
Show SMILES COc1ccc(NC(=O)c2ccccn2)cc1OC
Show InChI InChI=1S/C14H14N2O3/c1-18-12-7-6-10(9-13(12)19-2)16-14(17)11-5-3-4-8-15-11/h3-9H,1-2H3,(H,16,17)
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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

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PCBioAssay
n/an/an/an/a 3.65E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2VT1QHF
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50293717
PNG
(CHEMBL572346 | N-(3,4-dimethoxyphenyl)picolinamide...)
Show SMILES COc1ccc(NC(=O)c2ccccn2)cc1OC
Show InChI InChI=1S/C14H14N2O3/c1-18-12-7-6-10(9-13(12)19-2)16-14(17)11-5-3-4-8-15-11/h3-9H,1-2H3,(H,16,17)
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PC cid
PC sid
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Article
PubMed
n/an/an/an/a 2.40E+3n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium flux


J Med Chem 52: 4115-8 (2009)


Article DOI: 10.1021/jm9005065
BindingDB Entry DOI: 10.7270/Q2RJ4JHT
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50293717
PNG
(CHEMBL572346 | N-(3,4-dimethoxyphenyl)picolinamide...)
Show SMILES COc1ccc(NC(=O)c2ccccn2)cc1OC
Show InChI InChI=1S/C14H14N2O3/c1-18-12-7-6-10(9-13(12)19-2)16-14(17)11-5-3-4-8-15-11/h3-9H,1-2H3,(H,16,17)
PDB

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UniProtKB/TrEMBL

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/an/an/a>5.00E+3n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilization


J Med Chem 52: 4115-8 (2009)


Article DOI: 10.1021/jm9005065
BindingDB Entry DOI: 10.7270/Q2RJ4JHT
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293717
PNG
(CHEMBL572346 | N-(3,4-dimethoxyphenyl)picolinamide...)
Show SMILES COc1ccc(NC(=O)c2ccccn2)cc1OC
Show InChI InChI=1S/C14H14N2O3/c1-18-12-7-6-10(9-13(12)19-2)16-14(17)11-5-3-4-8-15-11/h3-9H,1-2H3,(H,16,17)
PDB

KEGG

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 2.35E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2DR2SWV
More data for this
Ligand-Target Pair