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3 similar compounds to monomer 58019

Compile data set for download or QSAR
Wt: 271.2
BDBM57949
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Wt: 321.3
BDBM65462
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Wt: 389.4
BDBM79637
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 57949,65462,79637   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
streptokinase A precursor


(Streptococcus pyogenes M1 GAS)
BDBM57949
PNG
(MLS000516225 | N-(4-pyridin-2-yl-1,3-thiazol-2-yl)...)
Show SMILES O=C(Nc1nc(cs1)-c1ccccn1)c1ccco1
Show InChI InChI=1S/C13H9N3O2S/c17-12(11-5-3-7-18-11)16-13-15-10(8-19-13)9-4-1-2-6-14-9/h1-8H,(H,15,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 1.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2736PBV
More data for this
Ligand-Target Pair
RPL19A


(Saccharomyces cerevisiae)
BDBM65462
PNG
(MLS000770462 | N-(4-pyridin-2-yl-1,3-thiazol-2-yl)...)
Show SMILES O=C(Nc1nc(cs1)-c1ccccn1)c1cc2ccccc2o1
Show InChI InChI=1S/C17H11N3O2S/c21-16(15-9-11-5-1-2-7-14(11)22-15)20-17-19-13(10-23-17)12-6-3-4-8-18-12/h1-10H,(H,19,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem

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PCBioAssay
n/an/an/an/a 1.17E+4n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2JQ0ZGP
More data for this
Ligand-Target Pair
BRCA1-associated RING domain protein 1


(Homo sapiens (Human))
BDBM79637
PNG
(5-(4-acetylphenyl)-N-(4-pyridin-2-yl-1,3-thiazol-2...)
Show SMILES CC(=O)c1ccc(cc1)-c1ccc(o1)C(=O)Nc1nc(cs1)-c1ccccn1
Show InChI InChI=1S/C21H15N3O3S/c1-13(25)14-5-7-15(8-6-14)18-9-10-19(27-18)20(26)24-21-23-17(12-28-21)16-4-2-3-11-22-16/h2-12H,1H3,(H,23,24,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

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PCBioAssay
n/an/a 4.85E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2DZ06SS
More data for this
Ligand-Target Pair
p53-Binding Protein HDMX


(Homo sapiens (Human))
BDBM79637
PNG
(5-(4-acetylphenyl)-N-(4-pyridin-2-yl-1,3-thiazol-2...)
Show SMILES CC(=O)c1ccc(cc1)-c1ccc(o1)C(=O)Nc1nc(cs1)-c1ccccn1
Show InChI InChI=1S/C21H15N3O3S/c1-13(25)14-5-7-15(8-6-14)18-9-10-19(27-18)20(26)24-21-23-17(12-28-21)16-4-2-3-11-22-16/h2-12H,1H3,(H,23,24,26)
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
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PCBioAssay
n/an/a 3.97E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2PG1Q6D
More data for this
Ligand-Target Pair
LAP4


(Saccharomyces cerevisiae)
BDBM65462
PNG
(MLS000770462 | N-(4-pyridin-2-yl-1,3-thiazol-2-yl)...)
Show SMILES O=C(Nc1nc(cs1)-c1ccccn1)c1cc2ccccc2o1
Show InChI InChI=1S/C17H11N3O2S/c21-16(15-9-11-5-1-2-7-14(11)22-15)20-17-19-13(10-23-17)12-6-3-4-8-18-12/h1-10H,(H,19,20,21)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 4.09E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q21R6P02
More data for this
Ligand-Target Pair