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Found 39 Enz. Inhib. hit(s) with Target = 'Apoptosis regulator BAX'
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50570680(CHEMBL4868313)
Affinity DataKi:  43nMAssay Description:Displacement of Bak BH3 domain peptide from human Bax by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078022(CHEMBL3417402)
Affinity DataKi:  800nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078029(CHEMBL3417409)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078015(CHEMBL3417395)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078027(CHEMBL3417407)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078028(CHEMBL3417408)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078026(CHEMBL3417406)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078024(CHEMBL3417404)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078030(CHEMBL3417410)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078023(CHEMBL3417403)
Affinity DataKi:  9.10E+3nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078018(CHEMBL3417398)
Affinity DataKi:  1.26E+4nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078017(CHEMBL3417397)
Affinity DataKi:  1.29E+4nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078016(CHEMBL3417396)
Affinity DataKi:  1.35E+4nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078019(CHEMBL3417399)
Affinity DataKi:  1.58E+4nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078025(CHEMBL3417405)
Affinity DataKi:  3.09E+4nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078020(CHEMBL3417400)
Affinity DataKi:  6.31E+4nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078021(CHEMBL3417401)
Affinity DataKi:  8.51E+4nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50516397(CHEMBL4579601)
Affinity DataIC50:  43nMAssay Description:Displacement of fluorescent Bak BH3 peptide domain from human recombinant Bax by competition fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547480(CHEMBL4790235)
Affinity DataIC50:  250nMAssay Description:Activation of BAX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50540081(CHEMBL4438921)
Affinity DataIC50:  3.00E+3nMAssay Description:Activation of Bax in human SMMC7721 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547494(CHEMBL4783072)
Affinity DataIC50:  3.30E+3nMAssay Description:Activation of BAX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078022(CHEMBL3417402)
Affinity DataEC50:  700nMAssay Description:Activation of Bax in human HuH7 cells assessed as inhibition of mitochondrial accumulation of fluorescent probe Mitotracker Red after 12 to 72 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547483(CHEMBL4778142)
Affinity DataEC50:  719nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547484(CHEMBL4780328)
Affinity DataEC50:  809nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547485(CHEMBL4753330)
Affinity DataEC50:  1.14E+3nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547479(CHEMBL4794290)
Affinity DataEC50:  393nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547486(CHEMBL4790418)
Affinity DataEC50:  2.22E+3nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547487(CHEMBL4761391)
Affinity DataEC50:  725nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547488(CHEMBL4797324)
Affinity DataEC50:  967nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547489(CHEMBL4758680)
Affinity DataEC50:  925nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547490(CHEMBL4756429)
Affinity DataEC50:  856nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547491(CHEMBL4784916)
Affinity DataEC50:  532nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547492(CHEMBL4779693)
Affinity DataEC50:  538nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547493(CHEMBL4776616)
Affinity DataEC50:  992nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547480(CHEMBL4790235)
Affinity DataEC50:  278nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataEC50: >1.00E+4nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50078015(CHEMBL3417395)
Affinity DataEC50:  8.20E+3nMAssay Description:Activation of Bax in human HuH7 cells assessed as inhibition of mitochondrial accumulation of fluorescent probe Mitotracker Red after 12 to 72 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547481(CHEMBL4777011)
Affinity DataEC50:  704nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
University Of Texas Medical Branch (Utmb)

Curated by ChEMBL
LigandPNGBDBM50547482(CHEMBL4754714)
Affinity DataEC50:  874nMAssay Description:Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed