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Found 137 Enz. Inhib. hit(s) with Target = 'Atrial natriuretic peptide receptor 1'
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091751(CHEMBL411542 | Cyclic-(Cys-Phe-Gly-Gly-Arg-Ile-Asp...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091758((S)-N-[(S)-4-Guanidino-1-((S)-2-methyl-butylcarbam...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091752((S)-3-{(2S,3S)-2-[(S)-5-Guanidino-2-(2-{4-[(naphth...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091757(CHEMBL264744 | Cyclic-(Cys-Phe-Gly-Gly-Ala-Ile-Asp...)
Affinity DataKi:  0.490nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091753(CHEMBL405854 | H-Ser-Leu-Arg-Arg-Ser-Ser-cyclic(Cy...)
Affinity DataKi:  0.650nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091761((S)-N-[(S)-4-Guanidino-1-((S)-2-methyl-butylcarbam...)
Affinity DataKi: >10nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091754(Arg-Ser-Ser-cyclic-(Cys-Phe-Gly-Gly-Arg-Ile-Asp-Ar...)
Affinity DataKi: >10nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091759(CHEMBL59028 | Naphthalene-2-carboxylic acid (4-{[(...)
Affinity DataKi:  62nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091747((S)-N-[(S)-1-((S)-2-Methyl-butylcarbamoyl)-ethyl]-...)
Affinity DataKi:  65nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091750(CHEMBL415133 | Cyclic-(Cys-Phe-Gly-Gly-Arg-Ile-Ala...)
Affinity DataKi:  87nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091749(CHEMBL412793 | Cyclic-(Cys-Phe-Gly-Gly-Arg-Ala-Asp...)
Affinity DataKi:  360nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091755((S)-N-[(S)-4-Guanidino-1-((S)-2-methyl-pentylcarba...)
Affinity DataKi:  539nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091748((S)-N-[(S)-4-Guanidino-1-((S)-2-methyl-butylcarbam...)
Affinity DataKi:  680nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091760((S)-N-((S)-1-Carbamoyl-4-guanidino-butyl)-3-{2-[(S...)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091756((S)-3-[(2S,3S)-2-((S)-2-Acetylamino-5-guanidino-pe...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254063(CHEMBL4102000)
Affinity DataIC50:  0.0940nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333671(CHEMBL1643388)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]ANP from NPR-A expressed in HeLa cells after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333672(CHEMBL1643389)
Affinity DataIC50:  60nMAssay Description:Displacement of [125I]ANP from NPR-A expressed in HeLa cells after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1/2/3(Homo sapiens (Human))
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM50228173(CHEMBL2371607)
Affinity DataIC50: >100nMAssay Description:Inhibitory activity against guanylate cyclase coupled receptor binding site in rabbit lung by using [125I]-ANP-(103-126)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254098(CHEMBL4098363)
Affinity DataIC50:  120nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333673(CHEMBL1643390)
Affinity DataIC50:  240nMAssay Description:Displacement of [125I]ANP from NPR-A expressed in HeLa cells after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254108(CHEMBL4062470)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254081(CHEMBL4103929)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254095(CHEMBL4084171)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254092(CHEMBL4062458)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254089(CHEMBL4081715)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254086(CHEMBL4076700)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254107(CHEMBL4105659)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254094(CHEMBL4076904)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254093(CHEMBL4071568)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254106(CHEMBL4084160)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254091(CHEMBL4061318)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254105(CHEMBL4076901)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254088(CHEMBL4088351)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254087(CHEMBL4075426)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254099(CHEMBL4092707)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254085(CHEMBL4097040)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254084(CHEMBL4087769)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254083(CHEMBL4076102)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254082(CHEMBL4073884)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254096(CHEMBL4099663)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254061(CHEMBL4089530)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254060(CHEMBL4061379)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254062(CHEMBL4060314)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112317(Atrial natriuretic peptide analogue | CHEMBL439465...)
Affinity DataEC50:  30nMAssay Description:Production of c-GMP in CHO cells expressing natriuretic peptide receptor (NPR-A) in response to compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112316(Atrial natriuretic peptide analogue | CHEMBL384862)
Affinity DataEC50:  8.30nMAssay Description:Production of c-GMP in CHO cells expressing natriuretic peptide receptor (NPR-A) in response to compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112318(Atrial natriuretic peptide analogue | CHEMBL409400)
Affinity DataEC50:  47nMAssay Description:Production of c-GMP in CHO cells expressing natriuretic peptide receptor (NPR-A) in response to compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112319(Atrial natriuretic peptide analogue | CHEMBL412345)
Affinity DataEC50: >1.00E+4nMAssay Description:Production of c-GMP in CHO cells expressing natriuretic peptide receptor (NPR-A) in response to compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112321(Atrial natriuretic peptide analogue | CHEMBL407206...)
Affinity DataEC50:  0.680nMAssay Description:Production of c-GMP in CHO cells expressing natriuretic peptide receptor (NPR-A) in response to compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112320(Atrial natriuretic peptide analogue | CHEMBL405572...)
Affinity DataEC50:  4.90nMAssay Description:Production of c-GMP in CHO cells expressing natriuretic peptide receptor (NPR-A) in response to compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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