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Found 11 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [696-1022,L858R]'
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute Of Science And Technology

US Patent
LigandPNGBDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)
Affinity DataIC50:  0.75nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute Of Science And Technology

US Patent
LigandPNGBDBM50289149(GW305074X | GW5074 | US10570155, GW5074 | US113324...)
Affinity DataIC50:  2.58nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute Of Science And Technology

US Patent
LigandPNGBDBM435711(US10570155, Compound 1II | US11332479, Compound 1I...)
Affinity DataIC50:  2.95nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute Of Science And Technology

US Patent
LigandPNGBDBM554465(US11332479, Compound 52III)
Affinity DataIC50:  5.41nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute Of Science And Technology

US Patent
LigandPNGBDBM554457(US11332479, Compound 31II)
Affinity DataIC50:  7.83nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute Of Science And Technology

US Patent
LigandPNGBDBM554458(US11332479, Compound 37III)
Affinity DataIC50:  13.8nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute Of Science And Technology

US Patent
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)
Affinity DataIC50:  48nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute Of Science And Technology

US Patent
LigandPNGBDBM26105(6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-[(1R...)
Affinity DataKd:  1.10nMpH: 7.4 T: 2°CAssay Description:The fluorescence buffer was degassed and aerated with pure nitrogen gas to remove dissolved oxygen. The assay was carried out on a FluoroMax-2 fluoro...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute Of Science And Technology

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataKd:  2.40nMpH: 7.4 T: 2°CAssay Description:The fluorescence buffer was degassed and aerated with pure nitrogen gas to remove dissolved oxygen. The assay was carried out on a FluoroMax-2 fluoro...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute Of Science And Technology

US Patent
LigandPNGBDBM26105(6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-[(1R...)
Affinity DataKd:  1.70nMpH: 7.4 T: 2°CAssay Description:The fluorescence buffer was degassed and aerated with pure nitrogen gas to remove dissolved oxygen. The assay was carried out on a FluoroMax-2 fluoro...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute Of Science And Technology

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataKd:  2.60nMpH: 7.4 T: 2°CAssay Description:The fluorescence buffer was degassed and aerated with pure nitrogen gas to remove dissolved oxygen. The assay was carried out on a FluoroMax-2 fluoro...More data for this Ligand-Target Pair