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Found 91 Enz. Inhib. hit(s) with Target = 'N(G),N(G)-dimethylarginine dimethylaminohydrolase 1'
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519933(CHEMBL4444007)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519934(CHEMBL4461206)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235685(hDDAH inhibitor, 1a)
Affinity DataKi:  2.00E+3nM ΔG°:  -33.8kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM92904(nNOS and DDAH inhibitor, 14)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519932(CHEMBL4449638)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM141899(US8921421, L-257 | hDDAH inhibitor, 2a)
Affinity DataKi:  1.30E+4nM IC50:  2.90E+4nMpH: 7.4Assay Description:This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM141899(US8921421, L-257 | hDDAH inhibitor, 2a)
Affinity DataKi:  1.30E+4nM ΔG°:  -29.0kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240959((S)-2-Amino-5-[N'-(2-methoxy-ethyl)-guanidino]-pen...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240959((S)-2-Amino-5-[N'-(2-methoxy-ethyl)-guanidino]-pen...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235691(hDDAH inhibitor, 2e)
Affinity DataKi:  1.70E+4nM ΔG°:  -28.3kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50254452(CHEMBL197234 | N-omega-propargyl-L-arginine)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM141900(US8921421, 3)
Affinity DataKi:  1.80E+4nM IC50:  7.00E+4nMpH: 7.4Assay Description:This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM141900(US8921421, 3)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM152700((S)-2-Amino-5-butyrimidamidopentanoic acid (9) | h...)
Affinity DataKi:  3.20E+4nM ΔG°:  -26.7kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50255074((S)-2-Amino-5-butyrimidoylamino-pentanoic acid | C...)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50254449(CHEMBL456882 | N5-(1-iminopent-3-enyl)-L-ornithine)
Affinity DataKi:  3.60E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235686(hDDAH inhibitor, 1c)
Affinity DataKi:  3.60E+4nM ΔG°:  -26.4kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50254450((S)-2-Amino-5-propionimidoylamino-pentanoic acid |...)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50254451(CHEMBL106423 | N-omega-(but-3-enyl)-L-arginine)
Affinity DataKi:  5.70E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50254451(CHEMBL106423 | N-omega-(but-3-enyl)-L-arginine)
Affinity DataKi:  5.70E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235690(hDDAH inhibitor, 2d)
Affinity DataKi:  5.70E+4nM ΔG°:  -25.2kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235689(hDDAH inhibitor, 2c)
Affinity DataKi:  5.80E+4nM ΔG°:  -25.2kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240714((2S)-5-{[(allylamino)(iminio)methyl]amino}-2-ammon...)
Affinity DataKi:  5.80E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519930(CHEMBL4544147)
Affinity DataKi:  5.90E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519936(CHEMBL4442120)
Affinity DataKi:  7.30E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235688(hDDAH inhibitor, 2b)
Affinity DataKi:  9.00E+4nM ΔG°:  -24.0kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240716((S)-2-Amino-5-(N'-propyl-guanidino)-pentanoic acid...)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM92905(DDAH Inhibitor, 15)
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataKi:  1.31E+5nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50254450((S)-2-Amino-5-propionimidoylamino-pentanoic acid |...)
Affinity DataKi:  1.45E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM152699((S)-2-Amino-5-propionimidamidopentanoic acid (8) |...)
Affinity DataKi:  1.45E+5nM ΔG°:  -22.8kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519935(CHEMBL4537472)
Affinity DataKi:  1.56E+5nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataKi:  2.90E+5nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519929(CHEMBL4517869)
Affinity DataKi:  4.89E+5nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM60960(hDDAH inhibitor, 2f)
Affinity DataKi:  6.06E+5nM ΔG°:  -19.1kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235693(hDDAH inhibitor, 2h)
Affinity DataKi:  7.64E+5nM ΔG°:  -18.5kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519928(CHEMBL4558445)
Affinity DataKi:  7.68E+5nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50404858(CHEMBL351569)
Affinity DataKi:  8.00E+5nMAssay Description:Competitive inhibition of human recombinant His6-tagged DDAH1 expressed in Escherichia coli BL21(DE3) using Nomega,Nomega-dimethyl-L-arginine as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519931(CHEMBL4554366)
Affinity DataKi:  9.83E+5nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50072297((S)-5-Acetimidoylamino-2-amino-pent | (S)-5-Acetim...)
Affinity DataKi:  9.90E+5nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM152697((S)-5-Acetimidamido-2-aminopentanoic acid (4, L-NI...)
Affinity DataKi:  1.16E+6nM ΔG°:  -17.4kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataKi:  1.20E+6nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataKi:  1.40E+6nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519939(CHEMBL4557528)
Affinity DataKi:  1.45E+6nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50421231(CHEMBL2087646)
Affinity DataKi:  1.70E+6nMAssay Description:Competitive inhibition of human recombinant His6-tagged DDAH1 expressed in Escherichia coli BL21(DE3) using Nomega,Nomega-dimethyl-L-arginine as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235692(hDDAH inhibitor, 2g)
Affinity DataKi:  1.97E+6nM ΔG°:  -16.1kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519938(CHEMBL4443195)
Affinity DataKi:  2.76E+6nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519937(CHEMBL4582190)
Affinity DataKi:  2.82E+6nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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