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Found 65 Enz. Inhib. hit(s) with Target = 'Dual specificity protein phosphatase 22'
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168874(3-{5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-4-oxo-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425807(CHEMBL2316902)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of VHX (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of VHX (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50556732(CHEMBL4750435)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of DUSP22 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205422(CHEMBL230941 | N3-cyclohexyl-N1-(2,3-di(furan-2-yl...)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205419(CHEMBL230472 | N3-butyl-N1-(2,3-di(furan-2-yl)quin...)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205439(CHEMBL230576 | N1-(2,3-di(furan-2-yl)quinoxalin-6-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168885(3-{5-[1-(4-Nitro-phenyl)-meth-(Z)-ylidene]-4-oxo-2...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205438(CHEMBL396800 | N3-butyl-N1-(2,3-di(furan-2-yl)quin...)
Affinity DataIC50:  2.79E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425808(CHEMBL2316906)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of VHX (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205426(CHEMBL230843 | N3-cyclopentyl-N1-(2,3-di(furan-2-y...)
Affinity DataIC50:  3.02E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168896(4-{5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-4-oxo-...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205428(CHEMBL230471 | N3-butyl-N1-(2,3-di(furan-2-yl)quin...)
Affinity DataIC50:  5.55E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168876(3-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168876(3-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168893(3-{5-[1-Cyclohexyl-meth-(Z)-ylidene]-4-oxo-2-thiox...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205429(CHEMBL425838 | N3-tert-butyl-N1-(2,3-di(furan-2-yl...)
Affinity DataIC50:  8.05E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205427(CHEMBL230681 | N1-(2,3-di(furan-2-yl)quinoxalin-6-...)
Affinity DataIC50:  8.36E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205432(CHEMBL446453 | N-(2,3-di(furan-2-yl)quinoxalin-6-y...)
Affinity DataIC50:  8.39E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM231167(US9340574, 7)
Affinity DataIC50: >1.00E+4nMpH: 7.0Assay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168894((4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-t...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168886(4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205425(CHEMBL230842 | N1-(2,3-di(furan-2-yl)quinoxalin-6-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168882(2-Hydroxy-4-{4-oxo-5-[1-phenyl-meth-(Z)-ylidene]-2...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168877(2-Hydroxy-5-{4-oxo-5-[1-phenyl-meth-(Z)-ylidene]-2...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168875(3-{4-Oxo-2-thioxo-5-[1-p-tolyl-meth-(Z)-ylidene]-t...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168881(4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168883((4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-t...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168878((3-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-t...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM82577((4-fluoro-1,3-benzothiazol-2-yl)-[5-(4-methoxyphen...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of recombinant VHX (unknown origin) using OMFP as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168897(3-{5-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-4-oxo...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205424(CHEMBL230258 | N1-(2,3-bis(4-fluorophenyl)quinoxal...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205423(CHEMBL230093 | N3-cyclopentyl-N1-(2,3-dip-tolylqui...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205421(CHEMBL395086 | N1-(2,3-di(furan-2-yl)quinoxalin-6-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205434(CHEMBL230207 | N1-(2,3-dip-tolylquinoxalin-6-yl)-N...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205433(CHEMBL230577 | N1-(2,3-di(furan-2-yl)quinoxalin-6-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205436(CHEMBL230362 | N-(2,3-bis(4-bromophenyl)quinoxalin...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205435(CHEMBL389107 | N-(2,3-diphenylquinoxalin-6-yl)-3-(...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205440(CHEMBL395085 | N1-(2,3-di(furan-2-yl)quinoxalin-6-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205431(CHEMBL230206 | N1-(2,3-diphenylquinoxalin-6-yl)-N3...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205437(CHEMBL439875 | N1-(2,3-bis(4-fluorophenyl)quinoxal...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205430(CHEMBL397726 | N1-(2,3-bis(4-bromophenyl)quinoxali...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM84581(Thioxothiazolidinone derivative, 1)
Affinity DataIC50: >5.00E+4nMpH: 6.0 T: 2°CAssay Description:PTP assay were conducted at 25 C in 96-well plates. Reaction rates were determined using a Variokan plate reader from Thermo Electron. For assay pH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168873(3-[4-Oxo-5-prop-(Z)-ylidene-2-thioxo-thiazolidin-3...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168887(4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50168889(3-Methyl-4-{4-oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-...)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50205420(CHEMBL230363 | N-(2,3-dimethoxyquinoxalin-6-yl)-3-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50262987(CHEMBL506661 | Illudalic acid)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LMWPTP (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50263036(3-Hydroxy-6-methoxy-8,8-dimethyl-1-oxo-1,3,4,7,8,9...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LMWPTP (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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