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Found 5 Enz. Inhib. hit(s) with Target = 'Glutamate--cysteine ligase catalytic subunit'
TargetGlutamate--cysteine ligase catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366432(CHEMBL1627263)
Affinity DataKi:  390nMAssay Description:Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 5.1 uMMore data for this Ligand-Target Pair
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TargetGlutamate--cysteine ligase catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287274((2S)-2-ammonio-4-[(2-carboxylatobutyl)phosphinato]...)
Affinity DataKi:  4.95E+3nMAssay Description:Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 5.7 uMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate--cysteine ligase catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287275(2-ammonio-4-[(2-carboxylatobutyl)sulfonyl]butanoat...)
Affinity DataKi:  9.23E+3nMAssay Description:Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 16.3 uMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate--cysteine ligase catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366433(CHEMBL1609891)
Affinity DataKi:  4.93E+4nMAssay Description:Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 25.0 uMMore data for this Ligand-Target Pair
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LigandPNGBDBM50487312(BUTHIONINE SULFOXIME)
Affinity DataKi:  1.30E+7nMAssay Description:Inhibition of Rattus norvegicus Wistar (rat) rat glutamate cysteine ligase using glutamate as substrate incubated for 10 min prior to substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article