TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli ass...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli ass...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.00400nMAssay Description:Inhibition of binding to Growth factor receptor bound protein 2 (Grb2) SH2 domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Binding affinity to Grb2 SH2 domain (unknown origin)More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of binding to Grb2 SH2 domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:In vitro Growth factor receptor bound protein 2-binding affinity of the compound was determined in in surface plasmon resonance (SPR) methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:In vitro Growth factor receptor bound protein 2-binding affinity of the compound was determined in in surface plasmon resonance (SPR) methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Growth factor receptor-bound protein 2 (Grb2) SH2 domain binding by ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-fused Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:In vitro binding affinity in extracellular ELISA-based assay for Grb2 SH2 domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition against Growth factor receptor bound protein 2 binding using ELISA techniqueMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibitory concentration against growth factor receptor bound protein 2More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of Growth factor receptor-bound protein 2 (Grb2) SH2 domain binding by ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Binding affinity to Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:In vitro Growth factor receptor bound protein 2-binding affinity of the compound was determined in ELISA methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibitory concentration against growth factor receptor bound protein 2More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration of the compound against Growth factor receptor bound protein 2 in MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of Growth factor receptor-bound protein 2 (Grb2) SH2 domain binding by ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Displacement of biotin-Ahx-PSpYVNVQN from Grb2-SH2 by competition binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration required against Src homology (SH2) domain of Growth factor receptor bound protein 2 by ELISA binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition against Growth factor receptor bound protein 2 binding using ELISA techniqueMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Growth factor receptor-bound protein 2 (Grb2) SH2 domain binding by ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Inhibitory concentration against growth factor receptor bound protein 2More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Inhibitory concentration against growth factor receptor bound protein 2More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Binding affinity for Growth factor receptor bound protein 2 SH2 domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:In vitro Growth factor receptor bound protein 2-binding affinity of the compound was determined in ELISA methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Grb2 by ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Grb2 SH2 domain bindingMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:The compound was evaluated for its potency to inhibit the interaction between Growth factor receptor bound protein 2 and phosphotyrosine-containing p...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration required against Src homology (SH2) domain of Growth factor receptor bound protein 2 by ELISA binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 12.1nMAssay Description:In vitro Growth factor receptor bound protein 2-binding affinity of the compound was determined in in surface plasmon resonance (SPR) methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Binding affinity to Grb2 SH2 domain (60 to 151) (unknown origin) expressed in Escherichia coli BL21(DE3) after overnight incubation by ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of Growth factor receptor-bound protein 2 (Grb2) SH2 domain binding by ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration against growth factor receptor bound protein 2More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair