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Found 119 Enz. Inhib. hit(s) with Target = 'Hemagglutinin'
TargetHemagglutinin(Influenza A virus (A/Shangdong/9/93(H3N2)))
Gilead Sciences

LigandPNGBDBM4934((2R,3R,4S)-4-carbamimidamido-3-acetamido-2-[(1R,2R...)
Affinity DataKi:  1nM ΔG°:  -53.4kJ/mole IC50:  5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails Article
TargetHemagglutinin(Influenza A virus (A/Shangdong/9/93(H3N2)))
Gilead Sciences

LigandPNGBDBM5210(3-carbamimidamido-4-acetamido-5-[(1S,2R)-1,2,3-tri...)
Affinity DataKi: >1.00E+5nM ΔG°: >-23.7kJ/mole IC50: >1.00E+5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails Article
TargetHemagglutinin()
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611021(US10626108, Compound 15)
Affinity DataIC50:  0.200nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin()
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611015(US10626108, Compound 13)
Affinity DataIC50:  1nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin()
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611022(US10626108, Compound 21)
Affinity DataIC50:  1nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin()
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611020(US10626108, Compound 14)
Affinity DataIC50:  2nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM5023((-)-(1R,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbuty...)
Affinity DataIC50:  2nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin()
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611029(US10626108, Compound 29)
Affinity DataIC50:  2nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM5024((-)-(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylb...)
Affinity DataIC50:  5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM5025(Oseltamivir | US10919856, POSITIVE CONTROL | ethyl...)
Affinity DataIC50:  5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin()
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611056(US10626108, Compound 36)
Affinity DataIC50:  7nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin()
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611028(US10626108, Compound 28)
Affinity DataIC50:  8nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM4934((2R,3R,4S)-4-carbamimidamido-3-acetamido-2-[(1R,2R...)
Affinity DataIC50:  17nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin()
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611026(US10626108, Compound 25)
Affinity DataIC50:  26nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain A/Aichi/2/1968 H3N2))
Individual

US Patent
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | 1-Adamanta...)
Affinity DataIC50:  30nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM5019((3R*,4R*)-3-[(1S*)-1-(Acetylamino)pentyl]-4-{[amin...)
Affinity DataIC50:  43nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin()
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611014(US10626108, Compound 6)
Affinity DataIC50:  130nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM5021((1R,3R,4R)-3-carbamimidamido-4-[(1S)-1-acetamidope...)
Affinity DataIC50:  412nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247019(US9701638, 10)
Affinity DataIC50:  560nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247018(US9701638, 9)
Affinity DataIC50:  560nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM5018((3R*,4R*)-3-[1-(Acetylamino)pentyl]-4-{[amino(imin...)
Affinity DataIC50:  893nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247021(US9701638, 12)
Affinity DataIC50:  1.10E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain A/Aichi/2/1968 H3N2))
Individual

US Patent
LigandPNGBDBM50280403(CHEMBL4163615)
Affinity DataIC50:  1.23E+3nMAssay Description:In vivo inhibition of leutenising hormone in rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247024(US9701638, 15)
Affinity DataIC50:  2.00E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain A/X-31 H3N2))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50402142(CHEMBL2207987)
Affinity DataIC50:  2.60E+3nMpH: 5.0Assay Description:Inhibition of hemagglutinin in Influenza A virus (A/X-31(H3N2)) infected in chicken red blood cells assessed as inhibition of hemolysis preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247017(US9701638, 8)
Affinity DataIC50:  3.30E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain A/X-31 H3N2))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50402143(CHEMBL2207978)
Affinity DataIC50:  3.70E+3nMpH: 5.0Assay Description:Inhibition of hemagglutinin in Influenza A virus (A/X-31(H3N2)) infected in chicken red blood cells assessed as inhibition of hemolysis preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain A/Aichi/2/1968 H3N2))
Individual

US Patent
LigandPNGBDBM50360450(CHEMBL1934618)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of Human influenza virus A/Aichi/2/68 (H3N2) hemagglutinin activity in chicken erythrocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247020(US9701638, 11)
Affinity DataIC50:  4.70E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM5020((1S,3R,4R)-3-carbamimidamido-4-[(1S)-1-acetamidope...)
Affinity DataIC50:  5.29E+3nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain A/Aichi/2/1968 H3N2))
Individual

US Patent
LigandPNGBDBM535848(US11241393, Sil 3)
Affinity DataIC50:  6.60E+3nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain A/Aichi/2/1968 H3N2))
Individual

US Patent
LigandPNGBDBM535847(US11241393, Sil 2)
Affinity DataIC50:  7.38E+3nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247013(US9701638, 4)
Affinity DataIC50:  7.40E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247014(US9701638, 5)
Affinity DataIC50:  7.60E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain A/Aichi/2/1968 H3N2))
Individual

US Patent
LigandPNGBDBM50360452(CHEMBL1934620)
Affinity DataIC50:  7.81E+3nMAssay Description:Inhibition of Human influenza virus A/Aichi/2/68 (H3N2) hemagglutinin activity in chicken erythrocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Saitama University

Curated by ChEMBL
LigandPNGBDBM50360452(CHEMBL1934620)
Affinity DataIC50:  7.81E+3nMAssay Description:Inhibition of Human influenza virus A/PR/8/34 (H1N1) hemagglutinin activity in chicken erythrocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Saitama University

Curated by ChEMBL
LigandPNGBDBM50360450(CHEMBL1934618)
Affinity DataIC50:  7.81E+3nMAssay Description:Inhibition of Human influenza virus A/PR/8/34 (H1N1) hemagglutinin activity in chicken erythrocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain A/Aichi/2/1968 H3N2))
Individual

US Patent
LigandPNGBDBM535849(US11241393, Sil 25)
Affinity DataIC50:  9.60E+3nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247015(US9701638, 6)
Affinity DataIC50:  1.06E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247016(US9701638, 7)
Affinity DataIC50:  1.08E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Saitama University

Curated by ChEMBL
LigandPNGBDBM50551836(CHEMBL3288937)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of Influenza A virus (A/PR 8/34 (H1N1)) hemagglutinin transfected in human HeLa cells assessed as reduction in low pH-indued polykaryon fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247012(US9701638, 3)
Affinity DataIC50:  1.22E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247025(US9701638, 16)
Affinity DataIC50:  1.32E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247022(US9701638, 13)
Affinity DataIC50: >2.00E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)
Affinity DataIC50:  2.40E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM5017((1R,3R,4S)-3-(Acetylamino-methyl)-4-guanidino-cycl...)
Affinity DataIC50:  2.67E+4nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM247011(US9701638, 2)
Affinity DataIC50:  5.30E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey

US Patent
LigandPNGBDBM31169(3-hydroxyquinolin-2(1H)-one, 23 | US9701638, 14)
Affinity DataIC50: >1.00E+5nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain A/Aichi/2/1968 H3N2))
Individual

US Patent
LigandPNGBDBM50360451(CHEMBL1934619)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of Human influenza virus A/Aichi/2/68 (H3N2) hemagglutinin activity in chicken erythrocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Saitama University

Curated by ChEMBL
LigandPNGBDBM50360451(CHEMBL1934619)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of Human influenza virus A/PR/8/34 (H1N1) hemagglutinin activity in chicken erythrocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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