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Found 16 Enz. Inhib. hit(s) with Target = 'Cation-independent mannose-6-phosphate receptor'
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM50373067(CHEMBL1162089)
Affinity DataIC50:  90nMAssay Description:Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM50373069(CHEMBL1162088)
Affinity DataIC50:  1.80E+3nMAssay Description:Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM50409194(CHEMBL39295)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of IGF-II stimulated MCF-7 human breast tumor cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM50373063(CHEMBL260987)
Affinity DataIC50:  3.70E+3nMAssay Description:Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM50373064(CHEMBL448108)
Affinity DataIC50:  4.44E+3nMAssay Description:Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM50373065(CHEMBL406598)
Affinity DataIC50:  4.76E+3nMAssay Description:Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM479364(US10894803, Compound 18 of the invention M6Pn-^...)
Affinity DataIC50:  5.00E+3nMAssay Description:96-Well plates (Maxisorp Nunc) are incubated overnight at 4° C. with 200 μl of PMP (pentamannose 6-phosphate) at the concentration of 200 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM50373070(CHEMBL261860)
Affinity DataIC50:  5.03E+3nMAssay Description:Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM50373066(CHEMBL257975)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM50275807(mannose 6-phosphate)
Affinity DataIC50:  1.15E+4nMAssay Description:Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM479366(US10894803, Compound 24 of the invention M6C-alpha...)
Affinity DataIC50:  1.70E+4nMAssay Description:96-Well plates (Maxisorp Nunc) are incubated overnight at 4° C. with 200 μl of PMP (pentamannose 6-phosphate) at the concentration of 200 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM50373068(CHEMBL1162087)
Affinity DataIC50:  2.00E+4nMAssay Description:Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM479365(US10894803, M6Pn-Ethyl-NH2)
Affinity DataIC50:  2.90E+4nMAssay Description:96-Well plates (Maxisorp Nunc) are incubated overnight at 4° C. with 200 μl of PMP (pentamannose 6-phosphate) at the concentration of 200 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM50409193(CHEMBL43417)
Affinity DataIC50:  4.65E+4nMAssay Description:Inhibition of IGF-II stimulated MCF-7 human breast tumor cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM50409195(CHEMBL43689)
Affinity DataIC50:  7.71E+4nMAssay Description:Inhibition of IGF-II stimulated MCF-7 human breast tumor cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCation-independent mannose-6-phosphate receptor(Homo sapiens (Human))
University Of Nebraska

Curated by ChEMBL
LigandPNGBDBM479367(US10894803, M6C-Ethyl-NH2)
Affinity DataIC50:  9.90E+4nMAssay Description:96-Well plates (Maxisorp Nunc) are incubated overnight at 4° C. with 200 μl of PMP (pentamannose 6-phosphate) at the concentration of 200 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent