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Found 98 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor antagonist protein'
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataKi:  11nMAssay Description:Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553093(CHEMBL4762305)
Affinity DataKi:  24nMAssay Description:Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553094(CHEMBL4761376)
Affinity DataKi: >100nMAssay Description:Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553090(CHEMBL4744066)
Affinity DataKi: >100nMAssay Description:Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553092(CHEMBL4753417)
Affinity DataKi:  201nMAssay Description:Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553095(CHEMBL4745618)
Affinity DataKi:  674nMAssay Description:Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553096(CHEMBL4787513)
Affinity DataKi:  887nMAssay Description:Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553091(CHEMBL4778960)
Affinity DataKi:  1.25E+3nMAssay Description:Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50529330(CHEMBL4527760)
Affinity DataKi:  1.30E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50529329(CHEMBL4560993)
Affinity DataKi:  3.20E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50529320(CHEMBL4540943)
Affinity DataKi:  3.80E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50529322(CHEMBL4466281)
Affinity DataKi:  4.60E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50529326(CHEMBL4557197)
Affinity DataKi:  5.70E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50529328(CHEMBL4475441)
Affinity DataKi:  8.70E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50529324(CHEMBL4445197)
Affinity DataKi:  1.30E+4nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50529325(CHEMBL4436776)
Affinity DataKi:  1.76E+4nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50:  2nMAssay Description:Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Leu-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601034(CHEMBL5191661)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50505155(CHEMBL4455644)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601033(CHEMBL5209483)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Arg-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601042(CHEMBL5195885)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50505150(CHEMBL4537224)
Affinity DataIC50:  32nMAssay Description:Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553093(CHEMBL4762305)
Affinity DataIC50:  39nMAssay Description:Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Mus musculus)
National Center For Scientific Research&Quot;Demokritos&Quot

Curated by ChEMBL
LigandPNGBDBM50077028(CHEMBL3416692)
Affinity DataIC50:  52nMAssay Description:Inhibition of mouse recombinant IRAP using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601035(CHEMBL5194003)
Affinity DataIC50:  150nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601032(CHEMBL5183817)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601040(CHEMBL5195928)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601031(CHEMBL5199194)
Affinity DataIC50:  240nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM85550(Ang IV | CAS_12676-15-2 | CHEMBL261120 | cid_12381...)
Affinity DataIC50:  251nMAssay Description:Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Leu-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601034(CHEMBL5191661)
Affinity DataIC50:  259nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in ovalbumin expressing wild type HEK293S cells assessed as decrease in antigen-mediated IL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601045(CHEMBL5209535)
Affinity DataIC50:  270nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601025(CHEMBL5207828)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601057(CHEMBL5171198)
Affinity DataIC50:  330nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553092(CHEMBL4753417)
Affinity DataIC50:  330nMAssay Description:Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601037(CHEMBL5200376)
Affinity DataIC50:  360nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601041(CHEMBL5197001)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601030(CHEMBL5185614)
Affinity DataIC50:  460nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601029(CHEMBL5194823)
Affinity DataIC50:  510nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601036(CHEMBL5184077)
Affinity DataIC50:  820nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601026(CHEMBL5202569)
Affinity DataIC50:  830nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553095(CHEMBL4745618)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553096(CHEMBL4787513)
Affinity DataIC50:  1.46E+3nMAssay Description:Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601056(CHEMBL5189714)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601055(CHEMBL5182525)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50601028(CHEMBL5174528)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553091(CHEMBL4778960)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50529330(CHEMBL4527760)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant IRAP expressed in baculovirus infected Sf9 cells using omniMMP fluorogenic substrate incubated for 5 to 10 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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