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Found 85 Enz. Inhib. hit(s) with Target = 'Kallikrein-6'
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588055(US11541023, Compound 3)
Affinity DataKi:  790nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50574434(CHEMBL4861066)
Affinity DataKi:  800nMAssay Description:Non-competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588057(US11541023, Compound 5)
Affinity DataKi:  1.00E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50574435(CHEMBL4862261)
Affinity DataKi:  1.00E+3nMAssay Description:Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50574432(CHEMBL4863108)
Affinity DataKi:  1.50E+3nMAssay Description:Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459512(CHEMBL4211240)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human KLK6 expressed in baculovirus/insect cell line system using Abz-KLRSSKQ-EDDnp substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588058(US11541023, Compound 6)
Affinity DataKi:  1.75E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588056(US11541023, Compound 4)
Affinity DataKi:  1.92E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50574431(CHEMBL4847066)
Affinity DataKi:  2.00E+3nMAssay Description:Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588054(US11541023, Compound 2)
Affinity DataKi:  2.26E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50574433(CHEMBL4852575)
Affinity DataKi:  2.40E+3nMAssay Description:Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50574430(CHEMBL4853943)
Affinity DataKi:  4.30E+3nMAssay Description:Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588053(US11541023, Compound 1)
Affinity DataKi:  4.44E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50256261(CHEMBL4059991)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged KLK6 isoform 1 (1 to 244 residues) expressed in HEK293 cells using fluorogenic Boc-QARAMC pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50256260(CHEMBL4094403)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50256262(CHEMBL4070056)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459537(CHEMBL4217078)
Affinity DataIC50:  18nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459539(CHEMBL4206734)
Affinity DataIC50:  23nMAssay Description:Inhibition of KLK6 (unknown origin) expressed in Pichia pastoris pre-incubated for 10 mins before Boc-ValProArg-AMC substrate addition and measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459525(CHEMBL4212718)
Affinity DataIC50:  100nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459515(CHEMBL4216138)
Affinity DataIC50:  100nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459538(CHEMBL4218203)
Affinity DataIC50:  130nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459545(CHEMBL4210314)
Affinity DataIC50:  130nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459527(CHEMBL4203947)
Affinity DataIC50:  150nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459508(CHEMBL4211164)
Affinity DataIC50:  190nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459535(CHEMBL4214705)
Affinity DataIC50:  250nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459531(CHEMBL4207925)
Affinity DataIC50:  250nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459522(CHEMBL4218314)
Affinity DataIC50:  290nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459538(CHEMBL4218203)
Affinity DataIC50:  470nMAssay Description:Inhibition of KLK6 (unknown origin) expressed in Pichia pastoris pre-incubated for 10 mins before Boc-ValProArg-AMC substrate addition and measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459516(CHEMBL4211677)
Affinity DataIC50:  490nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459511(CHEMBL4212332)
Affinity DataIC50:  640nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459529(CHEMBL4208878)
Affinity DataIC50:  890nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588055(US11541023, Compound 3)
Affinity DataIC50:  1.17E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459541(CHEMBL4204137)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459526(CHEMBL4218619)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588055(US11541023, Compound 3)
Affinity DataIC50:  1.23E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (PAR2) and 1 μl o...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459524(CHEMBL4215806)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50386418(CHEMBL2047313)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588054(US11541023, Compound 2)
Affinity DataIC50:  1.50E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588058(US11541023, Compound 6)
Affinity DataIC50:  1.56E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50574434(CHEMBL4861066)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of KLK6 (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459520(CHEMBL4203193)
Affinity DataIC50:  2.31E+3nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50574431(CHEMBL4847066)
Affinity DataIC50:  2.37E+3nMAssay Description:Inhibition of KLK6 (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588055(US11541023, Compound 3)
Affinity DataIC50:  2.38E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (MBP3) and 1 μl o...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588054(US11541023, Compound 2)
Affinity DataIC50:  2.63E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (PAR2) and 1 μl o...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459543(CHEMBL4203033)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50386416(CHEMBL2047314)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50574432(CHEMBL4863108)
Affinity DataIC50:  3.63E+3nMAssay Description:Inhibition of KLK6 (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588057(US11541023, Compound 5)
Affinity DataIC50:  3.74E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM50459507(CHEMBL4215383)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
Sarbonne Universite

US Patent
LigandPNGBDBM588056(US11541023, Compound 4)
Affinity DataIC50:  5.06E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (PAR2) and 1 μl o...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
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