Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-17'
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of MMP17 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50035507(CHEMBL3355722)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50035475(CHEMBL3355723)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146471(CHEMBL431226 | N-{1-(1,4-Dioxa-spiro[4.5]dec-8-yl)...)
Affinity DataIC50:  220nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146480(CHEMBL329967 | N-Hydroxy-N-{1-(4-hydroxyimino-cycl...)
Affinity DataIC50:  330nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146467(CHEMBL99365 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  350nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146478(CHEMBL98390 | N-Hydroxy-N-{1-(1-isobutyl-piperidin...)
Affinity DataIC50:  350nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146479(CHEMBL328645 | N-Hydroxy-N-{1-(4-hydroxyimino-cycl...)
Affinity DataIC50:  500nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146473(2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-a...)
Affinity DataIC50:  550nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146469(CHEMBL319782 | N-Hydroxy-N-[2-[4-(2-methyl-quinoli...)
Affinity DataIC50:  600nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146474(CHEMBL419896 | N-{2-(1,4-Dioxa-spiro[4.5]dec-8-yl)...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146470(CHEMBL328199 | N-Hydroxy-N-{1-(4-methylene-cyclohe...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146468(CHEMBL98852 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146477(CHEMBL99045 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146476(CHEMBL99995 | N-Hydroxy-N-{1-(4-hydroxyimino-cyclo...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50035472(CHEMBL3355724)
Affinity DataIC50:  3.26E+3nMAssay Description:Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146475(CHEMBL98202 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM400682(US10000476, Compound I-41)
Affinity DataIC50:  1.60E+4nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM400650(US10000476, Compound I-9)
Affinity DataIC50:  2.10E+4nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM400727(US10000476, Compound I-86)
Affinity DataIC50:  2.70E+4nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP17 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP17 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP17 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM400681(US10000476, Compound I-40)
Affinity DataIC50:  3.00E+4nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM400703(US10000476, Compound I-62)
Affinity DataIC50:  4.50E+4nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM400668(US10000476, Compound I-27)
Affinity DataIC50:  5.70E+4nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM400699(US10000476, Compound I-58 | US10000476, Compound I...)
Affinity DataIC50: >1.00E+5nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP17 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM400651(US10000476, Compound I-10 | US10000476, Compound I...)
Affinity DataIC50: >1.00E+5nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM400231(US10000476, Compound I-1 | US10000476, Compound I-...)
Affinity DataIC50: >1.00E+5nMAssay Description:MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent