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Found 628 Enz. Inhib. hit(s) with Target = 'Kelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2'
LigandPNGBDBM576177(WO2022056448, Compound 48)
Affinity DataIC50:  0.150nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576172(WO2022056448, Compound 43)
Affinity DataIC50:  0.200nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576170(WO2022056448, Compound 41)
Affinity DataIC50:  0.200nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576179(WO2022056448, Compound 50)
Affinity DataIC50:  0.25nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576162(WO2022056448, Compound 33)
Affinity DataIC50:  0.350nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576155(WO2022056448, Compound 26)
Affinity DataIC50:  0.350nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576156(WO2022056448, Compound 27)
Affinity DataIC50:  0.350nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576175(WO2022056448, Compound 46)
Affinity DataIC50:  0.350nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576167(WO2022056448, Compound 38)
Affinity DataIC50:  0.350nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576157(WO2022056448, Compound 28)
Affinity DataIC50:  0.450nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576178(WO2022056448, Compound 49)
Affinity DataIC50:  0.530nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576161(WO2022056448, Compound 32)
Affinity DataIC50:  0.550nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576166(WO2022056448, Compound 37)
Affinity DataIC50:  0.900nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576168(WO2022056448, Compound 39)
Affinity DataIC50:  1.05nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576163(WO2022056448, Compound 34)
Affinity DataIC50:  1.10nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576171(WO2022056448, Compound 42)
Affinity DataIC50:  1.15nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576160(WO2022056448, Compound 31)
Affinity DataIC50:  1.60nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576173(WO2022056448, Compound 44)
Affinity DataIC50:  5.90nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576165(WO2022056448, Compound 36)
Affinity DataIC50:  7.60nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576176(WO2022056448, Compound 47)
Affinity DataIC50:  26nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM576169(WO2022056448, Compound 40)
Affinity DataIC50:  50nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM561983(BDBM50369389 | US11396496, Compound A1)
Affinity DataIC50:  63nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
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LigandPNGBDBM561992(BDBM50537618 | US11396496, Compound B0)
Affinity DataIC50:  74nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
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LigandPNGBDBM415702(US10442759, Compound I-14)
Affinity DataIC50:  81nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM415703(US10442759, Compound I-15)
Affinity DataIC50:  84nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM415704(US10442759, Compound I-16)
Affinity DataIC50:  90nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM576159(WO2022056448, Compound 30)
Affinity DataIC50:  130nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM415707(US10442759, Compound I-19)
Affinity DataIC50:  140nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM576158(WO2022056448, Compound 29)
Affinity DataIC50:  147nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM561995(BDBM50538487 | US11396496, Compound C3)
Affinity DataIC50:  167nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
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LigandPNGBDBM561988(BDBM50537615 | US11396496, Compound A6)
Affinity DataIC50:  212nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
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LigandPNGBDBM576174(WO2022056448, Compound 45)
Affinity DataIC50:  236nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM415706(US10442759, Compound I-18)
Affinity DataIC50:  310nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM415705(US10442759, Compound I-17)
Affinity DataIC50:  320nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM415709(Ac-LDEETGEFL-OH | US10442759, Compound Nrf2 9mer ...)
Affinity DataIC50:  330nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM561987(BDBM50537610 | US11396496, Compound A5)
Affinity DataIC50:  350nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
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LigandPNGBDBM561986(BDBM50537611 | US11396496, Compound A4)
Affinity DataIC50:  530nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
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LigandPNGBDBM415691(US10442759, Compound I-3)
Affinity DataIC50:  580nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM415694(US10442759, Compound I-6)
Affinity DataIC50:  640nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM561994(BDBM50538480 | US11396496, Compound C2)
Affinity DataIC50:  698nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
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LigandPNGBDBM576164(WO2022056448, Compound 35)
Affinity DataIC50:  751nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair
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LigandPNGBDBM415700(US10442759, Compound I-12)
Affinity DataIC50:  830nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM415708(US10442759, Compound I-20)
Affinity DataIC50:  830nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM561996(US11396496, Compound C4)
Affinity DataIC50:  938nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
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LigandPNGBDBM415701(US10442759, Compound I-13)
Affinity DataIC50:  980nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM415692(US10442759, Compound I-4)
Affinity DataIC50:  980nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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LigandPNGBDBM561990(BDBM50537617 | BDBM561991 | US11396496, Compound A...)
Affinity DataIC50:  1.10E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
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LigandPNGBDBM561984(BDBM50537614 | US11396496, Compound A2)
Affinity DataIC50:  1.20E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
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LigandPNGBDBM561990(BDBM50537617 | BDBM561991 | US11396496, Compound A...)
Affinity DataIC50:  1.23E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
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LigandPNGBDBM415602(US10442759, Compound I-2)
Affinity DataIC50:  1.32E+3nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
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Displayed 1 to 50 (of 628 total ) | Next | Last >>
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