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Found 4 Enz. Inhib. hit(s) with Target = 'Nuclear factor of activated T-cells, cytoplasmic 2'
TargetNuclear factor of activated T-cells, cytoplasmic 2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387264(N-(3′- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxa...)
Affinity DataIC50: <500nMAssay Description:HEK 293 cells were stably transfected with a NFAT-Luc reporter gene. 30,000-80,000 cells were seeded per well. Test compounds from this invention wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear factor of activated T-cells, cytoplasmic 2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387280(N-(2,6- Difluorophenyl)-5-(2- methyl-3-(4-methyl- ...)
Affinity DataIC50: <500nMAssay Description:HEK 293 cells were stably transfected with a NFAT-Luc reporter gene. 30,000-80,000 cells were seeded per well. Test compounds from this invention wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear factor of activated T-cells, cytoplasmic 2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387273(US10292981, Example 135)
Affinity DataIC50: <500nMAssay Description:HEK 293 cells were stably transfected with a NFAT-Luc reporter gene. 30,000-80,000 cells were seeded per well. Test compounds from this invention wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear factor of activated T-cells, cytoplasmic 2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387315(4- Methyl-N-(2′-methyl- 3′-(4-methyl-5...)
Affinity DataIC50: <500nMAssay Description:HEK 293 cells were stably transfected with a NFAT-Luc reporter gene. 30,000-80,000 cells were seeded per well. Test compounds from this invention wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent