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Found 674 Enz. Inhib. hit(s) with Target = 'PAS domain-containing serine/threonine-protein kinase'
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50463479(CHEMBL4249925)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of PASK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50463483(CHEMBL4245242)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of PASK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human PASK using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  15.8nMAssay Description:Inhibition of human PASK using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154943(CHEMBL3775576)
Affinity DataIC50:  260nMAssay Description:Inhibition of PASK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463534(3-(Isopropyl(methyl)amino)-2-(4-(trifluoromethoxy)...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463535(2-(4-Cyanophenyl)-3-(isopropyl(methyl)amino)quinox...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463502(3-(Isopropyl(methyl)amino)-2-(pyridin-4-yl)quinoxa...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463503(2-(H-Imidazo[1,2-a]pyridin-6-yl)-3-(isopropyl(meth...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463504(2-(Benzofuran-2-yl)-3-(isopropyl(methyl)amino)quin...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463536((S)-2-(4-Fluorophenyl)-3-(2-methyl-4-(pyridin-2-yl...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463537((S)-2-(4-Fluorophenyl)-3-(2-methylpiperidin-1-yl)q...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463538(3-(Cyclopropyl(methyl)amino)-2-(4-fluorophenyl)qui...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463539((R)-2-(4-Fluorophenyl)-3-(2-(methoxymethyl)pyrroli...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463540((S)-3-(2-Methyl-4-(pyridin-2-yl)piperazin-1-yl)-2-...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463541(2-(Benzo[d][1,3]dioxol-5-yl)-3-(3,4-dihydroquinoli...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463542(3-(Octahydroquinolin-1(2H)-yl)-2-phenylquinoxaline...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463543(3-(Isopropyl(methyl)amino)-2-(pyridin-3-yl)quinoxa...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463544(US10781185, Example 98 | US11459307, Example 98)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463545(3-(Isopropyl(methyl)amino)-2-(quinolin-3-yl)quinox...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463546(3-(Isopropyl(methyl)amino)-2-(4-morpholinophenyl)q...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463547(3-(1,1-Dioxidothiomorpholino)-2-(4-fluorophenyl)qu...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463548(3-(1,1-Dioxidothiomorpholino)-2-phenylquinoxaline-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463549(2-(4-Fluorophenyl)-3-(3-oxopiperazin-1-yl)quinoxal...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463550(2-(4-Fluorophenyl)-3-(methyl(piperidin-4-yl)amino)...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463551(2-(4-Fluorophenyl)-3-(methyl(tetrahydro-2H-pyran-4...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463552(3-(Cyclopentyl(methyl)amino)-2-(4-fluorophenyl)qui...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463553(3-(Isopropyl(methyl)amino)-2-(5-methylthiophen-2-y...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463554(3-(Isopropyl(methyl)amino)-2-(thiophen-2-yl)quinox...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463555(2-(4-Fluorophenyl)-3-(4-(N-methylacetamido)piperid...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463556(2-(4-Fluorophenyl)-3-(4-methyl-3-oxopiperazin-1-yl...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463492((S)-2-(4-Fluorophenyl)-3-(2-methylpyrrolidin-1-yl)...)
Affinity DataIC50: <1.00E+3nMAssay Description:Purified PASK (UniProt # Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463500(2-(Benzo[d][1,3]dioxol-5-yl)-3-((S)-2-methylpyrrol...)
Affinity DataIC50: <1.00E+3nMAssay Description:Purified PASK (UniProt # Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463501(2-(1H-Indol-5-yl)-3-(isopropyl(methyl)amino)quinox...)
Affinity DataIC50: <1.00E+3nMAssay Description:Purified PASK (UniProt # Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463502(3-(Isopropyl(methyl)amino)-2-(pyridin-4-yl)quinoxa...)
Affinity DataIC50: <1.00E+3nMAssay Description:Purified PASK (UniProt # Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463503(2-(H-Imidazo[1,2-a]pyridin-6-yl)-3-(isopropyl(meth...)
Affinity DataIC50: <1.00E+3nMAssay Description:Purified PASK (UniProt # Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463504(2-(Benzofuran-2-yl)-3-(isopropyl(methyl)amino)quin...)
Affinity DataIC50: <1.00E+3nMAssay Description:Purified PASK (UniProt # Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463478(3-(4-(N-Methylmethan-3-ylsulfonamido)piperidin-1-y...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463505(3-(4-(Methylsulfonyl)piperazin-1-yl)-2-phenylquino...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463506(3-(4-(N-Methylacetamido)piperidin-1-yl)-2-phenylqu...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463507(3-(4-(Methyl(phenyl)amino)piperidin-1-yl)-2-phenyl...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463508(3-(Diethylamino)-2-phenylquinoxaline-6-carboxylic ...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463509(3-(4-Acetamidopiperidin-1-yl)-2-phenylquinoxaline-...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463510(3-(N-Methylmethan-5-ylsulfonamido)-2-phenylquinoxa...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463511(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-phenylquinox...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463479(3-(3,4-Dihydroquinolin-1(2H)-yl)-2-phenylquinoxali...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463512(3-(Phenethylamino)-2-phenylquinoxaline-6-carboxyli...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463513(3-(Methyl(phenethyl)amino)-2-phenylquinoxaline-6-c...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463480(3-(Isopropyl(methyl)amino)-2-phenylquinoxaline-6-c...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM463514(3-(Cyclohexylamino)-2-phenylquinoxaline-6-carboxyl...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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