Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'/cGMP-specific 3',5'-cyclic phosphodiesterase'
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataKi:  25nMAssay Description:Inhibition of recombinant human His6-tagged PDE5A (535 to 786 residues)/PDE6C expressed in Escherichia coli BL21-CodonPlus cells using [3H]cGMP as su...More data for this Ligand-Target Pair
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataKi:  25nMAssay Description:Inhibition of recombinant human His6-tagged PDE5A (535 to 786 residues)/PDE6C expressed in Escherichia coli BL21-CodonPlus cells using [3H]cGMP as su...More data for this Ligand-Target Pair
LigandPNGBDBM50027176(2-Acetoxy-Benzoic Acid | 3-Isobutyl-Methylxanthine...)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of recombinant human His6-tagged PDE5A (535 to 786 residues)/PDE6C expressed in Escherichia coli BL21-CodonPlus cells using [3H]cGMP as su...More data for this Ligand-Target Pair
LigandPNGBDBM50027176(2-Acetoxy-Benzoic Acid | 3-Isobutyl-Methylxanthine...)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of recombinant human His6-tagged PDE5A (535 to 786 residues)/PDE6C expressed in Escherichia coli BL21-CodonPlus cells using [3H]cGMP as su...More data for this Ligand-Target Pair