BindingDB PrimarySearch

Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Serine/threonine-protein kinase mTOR'

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Serine/threonine-protein kinase mTOR(Homo sapiens (Human))
University Of California San Francisco

BDBM36408(1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3...)

IC50: 1.70E+3nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay.More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

DrugBank MMDB PC cid PC sid PDB Similars

Details Article PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Serine/threonine-protein kinase mTOR(Homo sapiens (Human))
University Of California San Francisco

BDBM36409(2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin...)

IC50: 2.00E+3nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay.More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

Purchase MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)