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Found 344 Enz. Inhib. hit(s) with Target = 'Presequence protease, mitochondrial'
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622271((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-7-m...)
Affinity DataIC50:  5.20nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622271((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-7-m...)
Affinity DataIC50:  5.20nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622272((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-qui...)
Affinity DataIC50:  7.10nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622272((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-qui...)
Affinity DataIC50:  7.10nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM514515(US11096924, DASH-inhibitors 3102 C | US11583516, C...)
Affinity DataIC50:  15nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50:  23nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622160(US20230312550, Example 120)
Affinity DataIC50:  25nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622099(US20230312550, Example 59)
Affinity DataIC50:  30nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM514516(US11096924, DASH-inhibitors 4175 CH | US11583516, ...)
Affinity DataIC50:  34nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622227(US20230312550, Example 187)
Affinity DataIC50:  38nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM514514(US11096924, DASH-inhibitors (formerly 3102 A 2C) |...)
Affinity DataIC50:  42nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM514532(US11096924, DASH-inhibitors 3102 A | US11583516, C...)
Affinity DataIC50:  49nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  58nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50:  68nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622159(US20230312550, Example 119)
Affinity DataIC50:  76nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622236(US20230312550, Example 196)
Affinity DataIC50:  84nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622100(US20230312550, Example 60)
Affinity DataIC50:  86nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622263(US20230312550, Example 223)
Affinity DataIC50:  86nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622214(US20230312550, Example 174)
Affinity DataIC50:  87nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622161(US20230312550, Example 121)
Affinity DataIC50:  88nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622061(US20230312550, Example 21)
Affinity DataIC50:  93nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622105(US20230312550, Example 65)
Affinity DataIC50:  100nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622086(US20230312550, Example 46)
Affinity DataIC50:  110nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622168(US20230312550, Example 128)
Affinity DataIC50:  110nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622251(US20230312550, Example 211)
Affinity DataIC50:  110nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622165(US20230312550, Example 125)
Affinity DataIC50:  120nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622218(US20230312550, Example 178)
Affinity DataIC50:  120nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622225(US20230312550, Example 185)
Affinity DataIC50:  130nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622167(US20230312550, Example 127)
Affinity DataIC50:  130nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622155(US20230312550, Example 115)
Affinity DataIC50:  130nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622240(US20230312550, Example 200)
Affinity DataIC50:  130nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622091(US20230312550, Example 51)
Affinity DataIC50:  130nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622051(US20230312550, Example 11)
Affinity DataIC50:  140nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622223(US20230312550, Example 183)
Affinity DataIC50:  140nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622226(US20230312550, Example 186)
Affinity DataIC50:  150nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622057(US20230312550, Example 17)
Affinity DataIC50:  160nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622059(US20230312550, Example 19)
Affinity DataIC50:  160nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622063(US20230312550, Example 23)
Affinity DataIC50:  160nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622097(US20230312550, Example 57)
Affinity DataIC50:  160nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622088(US20230312550, Example 48)
Affinity DataIC50:  170nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622093(US20230312550, Example 53)
Affinity DataIC50:  170nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622140(US20230312550, Example 100)
Affinity DataIC50:  170nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622157(US20230312550, Example 117)
Affinity DataIC50:  170nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622239(US20230312550, Example 199)
Affinity DataIC50:  170nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622098(US20230312550, Example 58)
Affinity DataIC50:  180nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622256(US20230312550, Example 216)
Affinity DataIC50:  190nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622085(US20230312550, Example 45)
Affinity DataIC50:  190nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM514555(US11096924, DASH-inhibitors 4367 | US11583516, Cmp...)
Affinity DataIC50:  200nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622232(US20230312550, Example 192)
Affinity DataIC50:  200nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622046(US20230312550, Example 6)
Affinity DataIC50:  200nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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