Compile Data Set for Download or QSAR
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Found 70 Enz. Inhib. hit(s) with Target = 'Protein phosphatase 1B'
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50589477(CHEMBL5188453)
Affinity DataKi:  520nMAssay Description:Binding affinity to PPM1B (unknown origin) expressed in Escherichia coli BL21 assessed as inhibition constant using pNPP as substrate by absorbance b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135699((10S,13S,18S,19S,22R)-8-Isobutyl-18-((1E,3E)-(5S,6...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory concentration of the compound against protein phosphatase 1 (PP1) using phosphorylase-a assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135699((10S,13S,18S,19S,22R)-8-Isobutyl-18-((1E,3E)-(5S,6...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration of the compound against protein phosphatase 2A (PP2A) using phosphorylase-a assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50097634(CHEMBL158524 | OKADAIC ACID | okadaic acid analogu...)
Affinity DataIC50:  126nMAssay Description:Inhibitory concentration of the compound against Protein phosphatase 1(10 nM) isolated from rabbit muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50090505((1R,2S,6R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2...)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50366474(NORCANTHARIDIN)
Affinity DataIC50:  570nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135691((R)-2-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50090505((1R,2S,6R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2...)
Affinity DataIC50:  1.78E+3nMAssay Description:Inhibitory activity against recombinant Protein phosphatase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50366474(NORCANTHARIDIN)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibitory activity against recombinant Protein phosphatase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50106041((S)-2-((1S,2R,6S,7R)-3,5-Dioxo-10-oxa-4-aza-tricyc...)
Affinity DataIC50:  2.82E+3nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50090509((1R,4S)-7-Oxa-bicyclo[2.2.1]heptane-2,3-dicarboxyl...)
Affinity DataIC50:  2.96E+3nMAssay Description:Inhibitory activity against recombinant Protein phosphatase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50106047((R)-2-((1S,2R,6S,7R)-3,5-Dioxo-10-oxa-4-aza-tricyc...)
Affinity DataIC50:  3.22E+3nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50090502((1R,4S)-7-Oxa-bicyclo[2.2.1]heptane-2,3-dicarboxyl...)
Affinity DataIC50:  4.71E+3nMAssay Description:Inhibitory activity against recombinant Protein phosphatase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50090501((1R,4S)-7-Oxa-bicyclo[2.2.1]heptane-2,3-dicarboxyl...)
Affinity DataIC50:  4.82E+3nMAssay Description:Inhibitory activity against recombinant Protein phosphatase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50366474(NORCANTHARIDIN)
Affinity DataIC50:  5.31E+3nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135697(((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-methoxy-2,6...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibitory concentration of the compound against protein phosphatase 1 (PP1) using phosphorylase-a assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143522((1S,4R)-3-(3-Carboxy-phenylcarbamoyl)-7-oxa-bicycl...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143517((1S,4R)-3-(3-Methoxycarbonyl-phenylcarbamoyl)-7-ox...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143509((1S,4R)-3-Dimethylcarbamoyl-7-oxa-bicyclo[2.2.1]he...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135691((R)-2-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143515(Benzoic acid (1S,2R,6S,7R,8R)-3,5-dioxo-4,10-dioxa...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143516((1S,4R)-3-(4-Ethoxycarbonyl-phenylcarbamoyl)-7-oxa...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143512((1S,4R)-3-(4-Chloro-phenylcarbamoyl)-7-oxa-bicyclo...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135685((2S,5S)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-m...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135696((2R,5S)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-m...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135687((R)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Affinity DataIC50: >5.50E+4nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143514((1S,4R)-3-(3-Methoxycarbonyl-phenylcarbamoyl)-7-ox...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143520((1S,4R)-3-(4-Ethoxycarbonyl-phenylcarbamoyl)-7-oxa...)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50097633(CHEMBL2368224 | okadaic acid analogue)
Affinity DataIC50:  9.40E+4nMAssay Description:Inhibitory concentration of the compound against Protein phosphatase 1(10 nM) isolated from rabbit muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50106034((R)-2-((1S,2R,6S,7R)-3,5-Dioxo-10-oxa-4-aza-tricyc...)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143519(CHEMBL368167 | N-((1S,2R,7R)-3,5-Dioxo-4,10-dioxa-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135695((R)-2-[(4E,6E)-(2S,3S)-3-Acetylamino-7-(2-benzyl-p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135694((S)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143510((1S,4R)-3-(4-Chloro-phenylcarbamoyl)-7-oxa-bicyclo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135686((R)-2-((4E,6E)-(2S,3S)-3-Acetylamino-7-biphenyl-4-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135688((R)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135690(CHEMBL98661 | [((4E,6E)-(2S,3S,8S,9S)-3-Acetylamin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135689((2R,4R)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135693((2R,4S)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135692(CHEMBL100880 | N-[(2E,4E)-(1S,6S,7S)-7-Methoxy-4,6...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135684((S)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135683((2R,4R)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135682((2S,4R)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50135698((R)-2-((4E,6E)-(2S,3S)-3-Acetylamino-2,6-dimethyl-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) using pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143513((1S,4R)-3-Methylcarbamoyl-7-oxa-bicyclo[2.2.1]hept...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143521(CHEMBL368606 | N-((1S,2R,7R)-3,5-Dioxo-4,10-dioxa-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143518(((1R,6R,7S)-3,5-Dioxo-4,10-dioxa-tricyclo[5.2.1.0*...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50143511((1S,4R)-7-Oxa-bicyclo[2.2.1]heptane-2,3-dicarboxyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50106035((R)-2-((1S,2R,6S,7R)-3,5-Dioxo-10-oxa-4-aza-tricyc...)
Affinity DataIC50:  1.01E+5nMAssay Description:Inhibitory concentration against protein phosphatase 1 (PP1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1B(Homo sapiens (Human))
Oncowitan

Curated by ChEMBL
LigandPNGBDBM50564157(CHEMBL4792963)
Affinity DataIC50:  1.53E+5nMAssay Description:Inhibition of PPM1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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